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Corneal High Order Aberrations After Stream Light and Mechanical Photorefractive Keratectomy

Comparison of Corneal High Order Aberrations After Stream Light Trans-PRK and Mechanical Photorefractive Keratectomy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06110286
Enrollment
60
Registered
2023-10-31
Start date
2023-11-01
Completion date
2025-10-01
Last updated
2023-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Compare Corneal High Order Aberrations Before and After Stream Light Trans-PRK and Mechanical Photorefractive Keratectomy

Brief summary

Compare corneal high order aberrations before and after stream light trans-PRK and mechanical photorefractive keratectomy including third order aberrations; Trefoil and coma aberrations and forth order aberrations; spherical aberrations

Detailed description

Laser technology has played an important role in promoting the development of ophthalmology, especially corneal refractive surgery.1 Trans-epithelial photorefractive keratectomy (Trans-PRK) has become a highly researched topic in recent years.2 Different epithelial debridement methods with PRK showed favorable results for the surgical treatment of low to moderate myopia3. In mechanical PRK (m-PRK), epithelial debridement is achieved using a blunt spatula, whereas in stream light trans-PRK (t-PRK), there after an excimer laser is used to ablate corneal stroma3. The Stream Light t-PRK is a safe and effective treatment option for the correction of low to moderate myopia.4 Many studies have shown that the corneal asphericity developed significantly after refractive surgeries and introduce higher-order aberrations (HOAs).2 The present study focused on three of the most clinically important HOAs; spherical, coma, and trefoil aberrations, both preoperative and postoperative were recorded from topography over the 6-mm-diameter central corneal zone using Pentacam.

Interventions

Laser keratectomy by EX500 excimer laser after removal of corneal epithelium either mannually or by laser ablation

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* • Stable refraction for 1 year (refraction does not exceed 1D more than the last prescribed glasses). * Discontinuation of soft contact lens wears at least 1 week before examination. * Topography criteria: * Corneal thickness equal or more than 470 um * Symmetrical bow-tie * Back elevation not more than +12 * Normal Belin\\Ambrosio Enhanced ectasia display * Spherical equivalent not more than -6D.

Exclusion criteria

* • Previous ocular surgery * Concurrent ocular pathology; corneal scar, corneal dystrophy * Systemic disease; Uncontrolled diabetes, collagen disease * Post-operative complications; sub-epithelial haze.

Design outcomes

Primary

MeasureTime frameDescription
Corneal high order aberrations measured before and after the intervention by corneal topography machine1 monthe after surgery* Third order aberrations; Trefoil and coma aberrations * Forth order aberrations; spherical aberrations Trefoil, spherical and coma aberrations

Countries

Egypt

Contacts

Primary ContactEsraa R Mokhtar, master
esraarifaat89@gmail.com01064021834
Backup ContactKhaled A Mohamed, MD
abdelazeem..kh@gmil.com01123869699

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026