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Correlation Analysis Between Corneal Biomechanics and Anterior Segment

Correlation Analysis Between In-vivo Corneal Biomechanical Properties and Anterior Segment in Chinese Population

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06109636
Enrollment
50
Registered
2023-10-31
Start date
2023-03-04
Completion date
2023-10-01
Last updated
2023-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Sclera Thickness, CASIA2, Ciliary Muscle Thickness, Corneal Biomechanics

Brief summary

Evaluation of the ciliary muscle thickness, area, and anterior chamber angle, as well as anterior sclera thickness in subjects, to investigate the relationship between these measurements and corneal biomechanics. Clarify whether aqueous humor displacement, anterior sclera, and ciliary muscles influence the assessment of in vivo corneal biomechanics.

Interventions

scleral and ciliary muscle thickness were obtained by Casia2, biomechanical parameters were obtained by Pentacam and Corvis ST

Sponsors

Tianjin Eye Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

1. Best corrected visual acuity (BCVA) ≥ 20/20; 2. No other eye diseases except myopia and astigmatism; 3. The cornea was transparent, and there was no cloud or pannus;

Exclusion criteria

1. Corneal disease; 2. Ocular trauma; 3. Previous ocular surgery; 4. Any anterior segment diseases except cataract; 5. Patients were required to stop wearing soft contact lenses for at least 2 weeks and rigid contact lenses for at least 4 weeks before examination; 6. Pregnant and lactating women;

Design outcomes

Primary

MeasureTime frameDescription
scleral and ciliary muscle thicknessone yearThe thickness of scleral and ciliary muscle(Casia2, quantitative data through the utilization of its integrated ruler system)
biomechanical parametersone yearThe biomechanical parameters(Corvis ST, exporting the quality-assured csv files to analysis)

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026