Dengue, Hyponatremia, Inflammation
Conditions
Keywords
HYPONATREMIA, DENGUE, INFLAMMATION
Brief summary
Prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
Detailed description
Background Dengue infection is becoming more prevalent worldwide and is associated with systemic inflammation. Systemic Inflammation is associated with non-osmotic release of ADH. Methods: Participants conducted a prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
Interventions
OTHERhyponatremia
hyponatremia at admission in dengue infected patients
Sponsors
Hospital Nacional Profesor Alejandro Posadas
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Diagnosis confirmed by PCR, non structural protein 1 (NS1) antigen or IgM serology. Plasma sodium at admission.
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Admission to the hospital | between january 1, 2023 and november 1, 2023 | Risk for admission to the hospital |
Countries
Argentina
Contacts
Primary ContactCARLOS EGHI, MD
Backup ContactLADISLAO DIAZ BALLVE, PHD
Outcome results
None listed