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Dialysis Adequacy in Nutritional Status in Hemodialysis Patients

Effect of Dialysis Adequacy in Nutritional Status and Quality of Life in Hemodialysis Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06108856
Enrollment
200
Registered
2023-10-31
Start date
2023-12-01
Completion date
2025-01-31
Last updated
2023-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dialysis Adequacy

Brief summary

Assess nutrition status in hemodialysis patients and effect adequacy of hemodialysis on it. Effect of dialysis adequacy and nutritional status in patients' quality of life.

Detailed description

Patients with end-stage renal disease (ESRD) are unable to sustain life without hemodialysis. So, adequacy of hemodialysis is the main treatment for this patient. Adequacy of hemodialysis can be appeared on patient clinically by improve Quality of life and life expectancy, increase appetite and weight gain, control blood pressure, no bone disease, control of acidosis and anemia, Relief of uremic symptoms as nausea, vomiting, fatigue, anorexia, weight loss, muscle cramps, pruritus, or changes in mental status. Malnutrition is a major issue in patients undergoing hemodialysis and is observed in approximately 20% - 70% of this group. Malnutrition is a serious predictive factor for mortality and morbidity accompanied by an increase in the rate of hospitalization, less physical activity, lower quality of life. An imbalance between energy and protein gain and food metabolism, metabolic acidosis, dietary restrictions, anorexia and poor appetite, protein and nutrient loss during dialysis, underlying diseases, such as cardiovascular problems, infection, poor nutrition management, inadequate dialysis, etc. are among influencing factors on the nutrition of hemodialysis patients. Among patients undergoing hemodialysis, 6% to 8% suffer from severe malnutrition and 30% - 65% from mild malnutrition. The results of some studies have shown that one of the important causes of malnutrition is low dialysis adequacy in patients undergoing hemodialysis. Malnutrition is associated with an increase in morbidity, a decrease in functional capacity, and a greater number and duration of hospital admissions, all of which may cause a low health-related quality of life (QOL) and impact patients' emotional, physical, and psychosocial health.

Interventions

DEVICEHemodialysis machine

machine by which people undergo dialysis on it.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

1. Patients in regular haemodialysis . 2. patients above 18 years

Exclusion criteria

1. Patients with thyroid illness. 2. Patients with acute infection. 3. Patients with major surgeries. 4. Patients with malignancy. 5. Patients with liver cirrhosis. 6. patient with inflammatory bowel diseases.

Design outcomes

Primary

MeasureTime frameDescription
Effect of dialysis adequacy in nutritional status in haemodialysis patients by Body mass index (BMI) and Anthropometric measurements.baselineassess how dialysis adequacy affect nutritional status using : 1. Body mass index (BMI) : calculated based on the weight (kg)/height (m2) formula as it divide into : 1. underweight (BMI \< 18.5) worse outcome 2. normal weight (BMI from 18.5 to 25) better outcome . 3. overweight (BMI = 25 - 30). 4. obese (BMI \>30) . b)Anthropometric measurements : <!-- --> 1. weight in kilograms . 2. height in meters. 3. waist circumference in centimeters. 4. hip circumference in centimeters. 5. mid arm circumference in centimeters.

Contacts

Primary Contactgeorge san, Bachelor's
Georgesan264@gmail.com01017690272
Backup ContactMona soliman, professer
Solimanmona70@yahoo.com01005210950

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026