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Three-Axis Wearable Adaptive Vestibular Stimulator

3WAVeS: Three-Axis Wearable Adaptive Vestibular Stimulator

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06106256
Enrollment
40
Registered
2023-10-30
Start date
2023-11-15
Completion date
2026-12-01
Last updated
2026-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Motion Sickness

Brief summary

The purpose of this study is to improve current galvanic vestibular stimulation (GVS) technology to ease the motion sickness often associated with virtual reality (VR) simulation.

Detailed description

The Three-Axis Wearable Adaptive Vestibular Stimulator (3WAVeS) technology that combines galvanic vestibular stimulation (GVS) and Virtual Reality (VR) will not only increase VR-based simulation realism and presence, but will also mitigate the motion sickness often associated with VR simulation by re-coupling the vestibular and ocular inputs to the VR user. Additionally, due to GVS technology's ability to accurately provide continuous inputs to the vestibular system, 3WAVeS can intentionally simulate high-fidelity effects of spatial disorientation for training purposes.

Interventions

Four electrodes, forehead, behind both ears, and back of your neck, provide bidirectional electrical stimulation and receive information about the amplitude delivered accounting for skin impedance

OTHERFlight simulations in virtual reality (VR)

Highly immersive, 3D virtual flight simulation environment

OTHER3-DOF Bertec Portable Essential's dual-balance force plate system

Firm surface/plate to stand on while being presented disorienting visual patters of moving vertical and/or horizontal bars of alternating black and white.

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

Participants will be blinded to the galvanic stimulation (GVS) intervention.

Eligibility

Sex/Gender
ALL
Age
21 Years to 55 Years
Healthy volunteers
Yes

Inclusion criteria

* For our purposes, participants must be able to consent to participate themselves and be 21 to 55 years of age * Must be able to attend in-person sessions at the Mayo Aerospace Medicine and Vestibular Research Laboratory in Scottsdale, AZ. * No racial/ethnic groups will be excluded, although all participants must be fluent speakers of English.

Exclusion criteria

\- History of vestibular disease, migraine, or significant balance disorder; history of severe motion sensitivity, women who are pregnant.

Design outcomes

Primary

MeasureTime frameDescription
COG Sway velocityImmediately after balance testing in each session, approximately 1 hourThe sway angle of the center of gravity (COG) is the measure the amount of sway in any direction. The COG sway velocity is the ratio of the distance traveled by the COG (degrees) to the time (sec) of the trial.
Pensacola Diagnostic Index-based motion sickness questionnaireImmediately after each flight stimulation session, approximately 1 hourThis index allowed a comparison of motion sickness severity across subjects that may each present with a different constellation of symptoms like nausea, skin color, sweating, salivation, drowsiness, headache, and dizziness. The approach is to have the subject and/or observer grade the subjective intensity of different modalities of symptoms and signs (described below) as slight, moderate or severe. Overall motion sickness severity is then derived from a sum of scores resulting in a weighted "malaise index".

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORGaurav Pradhan, PhD

Mayo Clinic

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026