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EEG Characteristics and Postoperative Delirium

Correlation Between Intraoperative Electroencephalographic Signatures and Postoperative Delirium in Preoperative Frail Elderly Patients Undergoing

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06102967
Enrollment
66
Registered
2023-10-26
Start date
2023-10-01
Completion date
2024-07-01
Last updated
2024-08-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Function Abnormal, Frailty, Postoperative Delirium, PSI

Brief summary

The goal of this \[type of study: observational study \] is to \[compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.\] in \[describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis\]. The main question\[s\] it aims to answer are: • \[Is there any difference in the spectral range of EEG between POD patients and non POD patients\] Participants will \[Cognitive.•Postoperative delirium.•Preoperative weakness.\]

Detailed description

The goal of this \[type of study: observational study \] is to \[compare Correlation between EEG data and postoperative delirium in elderly patients undergoing colorectal cancer radical surgery under preoperative frailty monitoring.\] in \[describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis\]. The main question\[s\] it aims to answer are: • \[Is there any difference in the spectral range of EEG between POD patients and non POD patients\] Participants will \[Sedline EEG monitoring electrodes were placed 1cm above the eyebrows on both sides of the patient and at the temples on both sides, and were continuously monitored from the start of anesthesia in the operating room until the end of the surgery.Pay close attention to the vital signs and wait for the patient to fully recover and the vital signs to basically return to the preoperative level before returning to the ward.•Assessment of cognitive function using the Mini Mental State Scale (MMSE) 1 day before surgery and 7 days after surgery.•Preoperative assessment of frailty using the frailty screening scale.•Assess delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU) 1 day, 2 days, 3 days, and 7 days after surgery.\].

Interventions

BEHAVIORALdelirium

Evaluation of delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU) 1 day, 2 days, 3 days, and 7 days after surgery

Sponsors

Zhuo Liu
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* ASA I-III * The preoperative Frailty Scale (FRAIL) assessed frailty * The patient or his/her family is informed about the study and signs an informed consent form

Exclusion criteria

* Serious insufficiency of heart, liver, kidney and other functions * Those with a history of psychiatric or neurological illness, long-term use of psychotropic drug * History of cerebrovascular disease, brain trauma, or surgery * The patient was allergic to coupler or unable to place electrodes on the head * The patient was unable to complete the scale assessment as required.Patients with severe attention to hearing impairment were unable to complete the interview * The patient was diagnosed with delirium before surgery

Design outcomes

Primary

MeasureTime frameDescription
Postoperative delirium1 day, 2 days, 3 days, and 7 days after surgeryAssessing delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU)
EEG power of each bandDuring the procedureRecording frontal lobe electroencephalogram using a sedline root monitor (Masimo, Crop)
The number of minutes of suppression assessed by visual analysis of the EEGThroughout the operationThe burst suppression time was calculated by EEG visual analysis

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026