Survival and PN Dependence in SBS Patients

Long-term Survival and Parenteral Nutrition Dependence in Adult Patients With Non-malignant Short Bowel Syndrome

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06102668

Enrollment

173

Registered

2023-10-26

Start date

2012-01-01

Completion date

2019-01-01

Last updated

2023-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Short Bowel Syndrome

Brief summary

Short bowel syndrome (SBS) is a rare condition resulting from the loss of portions of the small intestine, and can cause a spectrum of metabolic and physiologic disturbances.The objective of this study was to determine the longterm survival and parenteral nutrition dependence of adult patients with SBS.

Detailed description

Short bowel syndrome (SBS), the most common form of intestinal failure, is a rare condition resulting from the loss of portions of the intestine, typically because of extensive surgical resection or loss of intestinal function. Patients with SBS often stuffer from intestinal insufficiency or intestinal failure because they are unable to maintain fluid and nutrient balances on a normal diet. SBS can cause various metabolic and physiologic disturbances. Although parenteral nutrition is a life-saving measure for many patients with SBS, patients with SBS is associated with decreased survival and parenteral nutrition (PN) dependence. Few studies have reported the survival and PN dependence in adult SBS patients in China.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

* Adult patients diagnosed with SBS.

Exclusion criteria

* age \<18 years; patients with active malignant tumors.

Design outcomes

Primary

Measure	Time frame	Description
Survival	2012/1/1-2019/1/1	Survival rate in patients with SBS
Parenteral nutrition dependence	2012/1/1-2019/1/1	Parenteral nutrition dependence in patients with SBS

Secondary

Measure	Time frame	Description
Risk factors	2012/1/1-2019/1/1	Risk factors of mortality and parenteral dependence in patients with SBS
Cause of death	2012/1/1-2019/1/1	Cause of death in patients with SBS at the end of follow-up

Outcome results