A Predictive Model for Early Metastasis in Cervical Cancer Patients After Radiotherapy

A Novel Predictive Model and Risk Stratification for Early Metastasis in Cervical Cancer Patients After Radiotherapy

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06101966

Enrollment

500

Registered

2023-10-26

Start date

2023-12-01

Completion date

2027-12-01

Last updated

2023-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer, Distant Metastasis, Prognostic Model, Radiotherapy, Risk Factor

Brief summary

This study aims to help to screen out appropriate cases for consolidation therapy and more intensive follow up.

Detailed description

Some cervical cancer patients experienced distant metastasis quickly after receiving complete radiotherapy and have a worse prognosis. However, there were few studies focused on these patients and with early distant metastasis. It is significant to predictive and screen out cervial cancer patients with a high risk of early metastasis for more comprehensive treatments and follow-up plans

Interventions

RADIATIONexternal pelvic beam radiotherapy (EBRT) followed by individualized high-dose-rate intracavitary brachytherapy (HDR-ICBT)

Radical RT consisted of external pelvic beam radiotherapy (EBRT) and individualized high-dose-rate intracavitary brachytherapy (HDR-ICBT).Cisplatin-based concurrent chemoradiotherapy (CCRT) was recommended for CC patients unless for economic status, age consideration and patients' desires.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 85 Years

Healthy volunteers

Inclusion criteria

* patients confirmed as cervical cancer by biopsies and treated with radiotherapy were initially enrolled

Exclusion criteria

* (1) patients treated with surgery. (2) patient received incomplete treatment somewhere else. (3) patients with cancer history. (4) patients with pelvic surgery history. (5) patients without complete pre-treatment medical information. (6) patients with unfinished radical radiotherapy. (7) patients suffered from metastasis within 3 months after radiotherapy. (8) patients without complete 1-year follow-up materials

Design outcomes

Primary

Measure	Time frame	Description
Early distant metastases	3-12months	Early distant metastasis defines as metastasis occurrence between 3 -12 months after radiotherapy.

Countries

China

Contacts

Primary ContactYang Sun, PhD

sunyang@fjzlhospital.com+8615959028989

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026