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Veterans Affairs Pharmacist Heart Failure Medication Titration Project 1

Randomized Evaluation of Audit and Feedback Intervention to Promote Pharmacist Heart Failure Medication Titration in Veterans Affairs Sierra Pacific Network

Status
Enrolling by invitation
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06099808
Enrollment
110
Registered
2023-10-25
Start date
2023-11-20
Completion date
2024-09-30
Last updated
2024-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure

Keywords

Pharmacist, Medication therapy

Brief summary

This is a randomized quality improvement project to evaluate the impact of an audit and feedback intervention to motivate pharmacists to provide heart failure (HF) medication management to patients in the Veterans Health Administration (VHA) Sierra Pacific region (VISN 21). The results of this project could provide guidance for how to successfully scale a pharmacist-based HF remote management program in the VHA more broadly. Pharmacists providing clinical care as part of Patient Aligned Care Team (PACT) within VHA VISN 21 will be included. Pharmacists will be randomized to one of 3 arms in a 1:1:2 ratio: (1) monthly audit and feedback of HF medication titration activities (AF) vs. (2) educational resources and monthly notification of HF medication titration actions in addition to a list of potential patients for HF optimization (AF+) vs. (3) usual care without audit and feedback (UC). Pharmacists across all three arms will be given access to shared educational resources on HF pharmacist care and educational webinars. Six months after the intervention, rates of pharmacist HF medication titration encounters will be compared among the 3 groups.

Interventions

OTHERAudit and Feedback Emails

Monthly email containing information including their total medication titration encounters over a 3 month period, as well as the site and VISN level for comparison. This will include rates of GDMT utilization and percentage of patients on \>50% of the target dose of GDMT stratified by site, VISN and national. This data will be obtained from VHA national HF dashboard.

OTHERPatient Specific Targets

Monthly emails include a list of 5-7 HF patients who are potentially eligible for pharmacist HF medication titration. This data will be obtained from VHA national HF dashboard.

OTHEREducational Resources

Monthly educational webinars on pharmacist HF management and access to material and protocols on HF medication management.

Sponsors

VA Palo Alto Health Care System
CollaboratorFED
Stanford University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Clinical pharmacists in the Veterans Health Administration that provide Patient Aligned Care Team (PACT) care in VA Sierra Pacific Network (VISN 21)

Exclusion criteria

* Excluded per pharmacist supervisor decision

Design outcomes

Primary

MeasureTime frameDescription
Number of monthly heart failure medication adjustment encounters2 months post-randomization to 6 months post-randomizationEncounters in which pharmacist adjusted heart failure medications

Secondary

MeasureTime frameDescription
Number of new patients with pharmacist HF managementWithin 6 months post-randomizationFor each pharmacist, will calculate the number of patients with heart failure in their panel that receive care from pharmacist that were not receiving care prior to randomization
Guideline medical therapy scoreAt 6 months post randomizationComposite score of heart failure medical therapy among patients with heart failure for patients within each pharmacists panel
Beta-blocker therapyAt 6 months post randomizationPercentage of patients with heart failure with reduced ejection fraction in each pharmacist panel that are treated with beta-blocker therapy
Percentage of heart failure patients with medication management by pharmacistWithin 6 months post-randomizationFor each pharmacist, will calculate the percentage of patients with heart failure in their panel that receive medication adjustments from pharmacist
Angiotensin receptor neprilysin inhibitor (ARNI) therapyAt 6 months post randomizationPercentage of patients with heart failure with reduced ejection fraction in each pharmacist panel that are treated with ARNI therapy
Mineralocorticoid receptor antagonist (MRA) therapyAt 6 months post randomizationPercentage of patients with heart failure in each pharmacist panel that are treated with MRA therapy
Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2i) therapyAt 6 months post randomizationPercentage of patients with heart failure in each pharmacist panel that are treated with SGLT2i therapy
Renin-angiotensin system inhibitor (RASI) therapyAt 6 months post randomizationPercentage of patients with heart failure with reduced ejection fraction in each pharmacist panel that are treated with RASI therapy

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026