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Electrolytes Disturbances in Critically Ill Egyptian Patients

The Incidence, Risk Factors and Outcomes of Electrolytes Disturbances in Critically Ill Egyptian Patients: A Single-Centre Prospective Cohort Study

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06097104
Enrollment
110
Registered
2023-10-24
Start date
2023-09-26
Completion date
2024-08-08
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electrolyte Imbalance

Keywords

Electrolytes, Egyptian

Brief summary

All selected individuals will be subjected to the following: 1. Full medical history taking 2. Full clinical examination, APACHE II score on admission 3. Electrolytes panel daily on ICU admission 4. Estimate the duration of stay at ICU Also all selected individuals will be sectioned into groups regarding sites of collection (surgical ICU, CCU and medical ICU). All collected individuals will be sectioned regarding electrolytes imbalance into mild, moderate and severe groups

Detailed description

Study Procedures: All selected individuals will be suffering from electrolyte imbalance (EI) with the following data will be obtained: o Measurements: 1. Demographic data: age - gender - BMI - electrolytes data on ICU admission 2. Vital data: heart rate - respiratory rate - blood pressure measurement - Oxygen saturation - Urinary output - Temp +/- CVP measurement. 3. Lab.: CBC - Kidney function tests - liver function tests - ABG - levels of serum sodium, potassium, magnesium, phosphorus, ionized calcium and chloride, with maximum 5 mm blood sampling per day. Serum-sodium levels will be corrected for serum-glucose by lowering the sodium concentration by 2.4 mmol/L for every 100 mg/dl increase in glucose. Corrected Sodium = Measured sodium + 0.016 (Serum glucose - 100) A correction formula was also used to calculate albumin-corrected calcium levels (mmol/L) Corrected Calcium = (0.8 (Normal Albumin - Pt's Albumin)) + Serum Ca 4. APACHE II score 5. Comorbidities 6. Complications: AKI- Acute myocardial infarction 7. Duration of ICU stay 8. Duration of hospital stay 9. Outcome (regarding eventual complications: AKI- Acute myocardial infarction)

Interventions

OTHERelectrolytes - serum blood samples

CBC - Kidney function tests - liver function tests - ABG - levels of serum sodium, potassium, magnesium, phosphorus, ionized calcium and chloride, with maximum 5 mm blood sampling per day

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

\- All patients admitted to medical ICU, surgical ICU and CCU suffering from electrolyte imbalance (EI) over 18 years with the comorbid conditions : 1. Hypertension 2. Heart failure 3. Chronic chest diseases 4. Cancers 5. Chronic kidney disease 6. Diabetes mellitus 7. Cardiac dysrhythmias 8. Pneumonia 9. Sepsis 10. Dehydration 11. Critical bones fractures

Exclusion criteria

* Patients with 1. Age less than 18 year old 2. Patient or his 1st degree relatives refuse to participate 3. Patients without electrolytes data 4. Current smoking

Design outcomes

Primary

MeasureTime frameDescription
impact of electrolytes imbalances for general health status1 yearLaboratory: levels of serum sodium mmol/L, potassium mmol/L, magnesium mg/dl, phosphorus mg/dl, ionized calcium mmol/L and chloride mmol/L, with maximum 5 mm blood sampling per day. Serum-sodium levels will be corrected for serum-glucose by lowering the sodium concentration by 2.4 mmol/L for every 100 mg/dl increase in glucose. Corrected Sodium = Measured sodium + 0.016 (Serum glucose - 100). A correction formula was also used to calculate albumin-corrected calcium levels (mmol/L). Corrected Calcium = (0.8 (Normal Albumin - Pt's Albumin)) + Serum Ca

Secondary

MeasureTime frameDescription
impact of electrolytes imbalances for hospital stay1 yearcalculation of hospital admission days and correlations with records of serum electrolytes results per admission

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026