Healthy
Conditions
Keywords
exercise, muscle cross-sectional area, intramyocellular lipids, extramyocellular lipids, strength
Brief summary
The project is going to examine the effects of resistance exercise training in prepubescent youth on skeletal muscle strength and lipid content.
Interventions
Participants will strength train via linear periodization resistance exercise training.
Sponsors
Study design
Eligibility
Inclusion criteria
* Healthy volunteer males and females ages 8 - 10 years.
Exclusion criteria
* No history or ongoing neuromuscular diseases. * No history or ongoing musculoskeletal injuries. * No history or ongoing disease that effects metabolism.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the muscular strength of leg extensors, as measured with isotonic strength. | baseline, following the intervention (9 weeks) | The score will reflect the strength of the leg extensors. The higher score, reflects greater muscular strength. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in thigh muscle cross-sectional area. | baseline, following the intervention (9 weeks) | Scores are measured cross-sectional area from ultrasound images. The higher score, reflects greater muscle size of the leg extensors. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a concentration. The higher score, reflects more fat in the fibers. |
| Change from baseline in extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a concentration. The higher score, reflects more fat in the fibers. |
| Change from baseline in the fatty acid saturation levels of the extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a saturation level of fatty acids in the extramyocellular lipid. The higher score, reflects greater fatty acid saturation. |
| Change from baseline in the fatty acid saturation levels of the intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a saturation level of fatty acids in the intramyocellular lipid. The higher score, reflects greater fatty acid saturation. |
Countries
United States