Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum

Predictors of Disease Free Survival After Curative Cancer Rectum Surgery

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06096493

Enrollment

200

Registered

2023-10-23

Start date

2023-05-01

Completion date

2023-12-31

Last updated

2023-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Cancer

Keywords

cancer rectum, recurrence, disease free survival

Brief summary

Tumor recurrence after curative surgical resection for rectal cancer is a serious complication that greatly affects the overall morbidity and the outcome. This study aims to identify the different prognostic factors affecting recurrence and disease-free survival after surgery.

Detailed description

A retrospective analysis of patients operated for cancer rectum with curative intent from. Exclusion criteria will include patients with familial adenomatous polyposis, multiple synchronous or metachronous rectal cancers, and death within 3 months. Incomplete patients' files and patients that lost follow-up will be excluded. Demographic, histopathological, follow up and outcome data will be collected from completed patients' files. Demographics include age, gender, family history, and chief complaint at the presentation. Histopathological data include tumor grade, vascular-perineural invasion, the total number of lymph nodes removed, and positive lymph nodes. Lymph node ratio will be defined as the ratio of positive lymph nodes to the total number of retrieved lymph nodes in a histopathology specimen. Disease-free survival will be calculated for each patient based on the time of surgery to the time of recurrence detection.

Interventions

PROCEDUREcurative surgery for cancer rectum

Curative surgery for cancer rectum.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Inclusion criteria

* Patients who had curative surgery for cancer rectum.

Exclusion criteria

* Patients with familial adenomatous polyposis (FAP), multiple synchronous or metachronous rectal cancers, and death within 3 months * Patients that lost follow-up will be excluded.

Design outcomes

Primary

Measure	Time frame	Description
Disease free survival.	up to 5 years	From date of surgery until the date of recurrence detection.
Tumor recurrence	Through study completion, an average of 3 year	Presence of Tumor recurrence after curative surgery for cancer rectum.

Countries

Egypt

Contacts

Primary ContactAbdallah M Taha, MD

abdallahsurgery@med.svu.edu.eg+201011716497

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026