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The Implementation of Early Mobilization and Chest Physiotherapy on Weaning Rate of Prolong Weaning Patients.

The Implementation of Early Mobilization and Chest Physiotherapy on Weaning Rate of Prolong Weaning Patients. A Retrospective Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06095609
Enrollment
202
Registered
2023-10-23
Start date
2022-06-01
Completion date
2022-06-19
Last updated
2023-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolonged Weaning, Early Mobilization, Chest Physiotherapy

Brief summary

Weaning from mechanical ventilator is essential to liberate patients to normal life. Prolong weaning is defined as failure of 3 times spontaneous breath trial (SBT) and requiring more than 7 days weaning from mechanical ventilation after first SBT. higher unsuccessful rate of extubation and higher mortality rate. Possible reasons to cause prolong weaning could be attributed to intensive care unit acquired weakness (ICU-AW) and poor lung hygiene. In order to solve these two problems and increase the weaning rate, early mobilization (EM) and chest physiotherapy (CPT) are considered as possible strategy to attain the goal. According to previous articles, lacking of control group and small sample size made it difficult to confirm the true effect of EM and CPT on prolong weaning patients. Thus, the aims of this articles are discussing the influence from EM with CPT on weaning rate and other hospitalization outcomes with larger sample sizes and control group.

Interventions

OTHEREarly mobilization plus chest physiotherapy

Early mobilization:early mobilization has been confirmed its positive effectiveness on cutting down the MV use days and mortality rate, attenuating the side effect such as muscle strength loss and functional activity dysfunction resulting from ICU acquired weakness among the patients with mechanical ventilation. Chest physiotherapy:a common technique to reduce the respiratory complications in ICU, has been proved certain positive influence on airway clearance and hospital lengths of stay.

Sponsors

Taoyuan General Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

The study retrospectively reviewed the medical record from the medical team. Patients before 2019/01/01 who didn't receive physiotherapy are regarded as control group. Patients after 2019/01/01 are assigned to the experiment group.

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* The subjects' data which met the inclusion criteria are: 1. Age\>20 2. Patient with or without 3. Patient who met the criteria of received physiotherapy (Figure 1.) 4. No usage of life support device such as ECMO and so on. 5. Continuous mechanical ventilator use over 21 days.

Exclusion criteria

* The

Design outcomes

Primary

MeasureTime frameDescription
Weaning success rateup to 6 weeks in respiratory care centerWeaning success was defined as patients being free from MV or BiPAP for 5 days based on Taiwan

Secondary

MeasureTime frameDescription
hospital mortality rateup to 6 weeks in respiratory care centerthe mortality rate during the hospital course
discharge to home rateafter 6 weeks in respiratory care centerThe rate of going home after discharge
RCC mortality rateup to 6 weeks in respiratory care centerthe mortality rate of respiratory care center
RCC days of stayup to 6 weeks in respiratory care centerThe days staying in respiratory care center
total hospital days of stayup to 10 weeks in the hospitalThe days staying in the hospital
total mechanical ventilator useup to 6 weeks in respiratory care centerThe days of mechanical use during the admission time

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026