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Application of Unilateral Epidural Anesthesia in Older Patients With Hip Fracture

Application of Unilateral Epidural Anesthesia in Older Patients With Hip Fracture

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06093412
Enrollment
106
Registered
2023-10-23
Start date
2018-01-01
Completion date
2021-06-30
Last updated
2023-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Anesthesia

Keywords

unilateral epidural anesthesia, combined lumbar and epidural anesthesia

Brief summary

Because of population ageing, fragility fractures have become a huge burden on healthcare systems and wider society. Fractures result in a sharp drop in both short-term and long-term quality of life, they have a strong influence on activities of daily living and mobility, and they are associated with a significant increase in 1-year mortality (18%-36%). Surgery can benefit elderly patients with hip fractures to an extent, but it entails inevitable risks, particularly with respect to general anesthesia. In recent years unilateral spinal anesthesia has attracted attention due to the advantages of hemodynamic stability, reduced anesthetic dosage, and sufficient sensory block. On the basis of a previous study, in the current study anesthetics were directly implanted into the unilateral epidural space in elderly patients with hip fractures prior to the completion of surgery. Data from 106 patients with old hip fractures who had undergone surgical treatment incorporating unilateral epidural anesthesia (UEA) or combined lumbar and epidural anesthesia were retrospectively analyzed in an attempt to provide a feasible solution for this kind of patients' anesthesia.

Detailed description

Surgery can benefit elderly patients with hip fractures to an extent, but it entails inevitable risks, particularly with respect to general anesthesia. In recent years unilateral spinal anesthesia has attracted attention due to the advantages of hemodynamic stability, reduced anesthetic dosage, and sufficient sensory block. On the basis of a previous study, in the current study anesthetics were directly implanted into the unilateral epidural space in elderly patients with hip fractures prior to the completion of surgery.

Interventions

The patients received unilateral epidural anesthesia

PROCEDUREcombined lumbar and epidural anesthesia

The patients received combined lumbar and epidural anesthesia

Sponsors

Sichuan Provincial People's Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
66 Years to 94 Years
Healthy volunteers
No

Inclusion criteria

had a fracture of a proximal femur were aged \> 65 years the fracture occurred within 2 weeks of receiving treatment with comorbidities including pulmonary disease, arrhythmia, senile valve disease or lacunar infarction underwent intraspinal anesthesia during surgery

Exclusion criteria

had a secondary fracture after endoprosthetic reconstruction or intramedullary nail had a pathological fracture caused by tumor or tuberculosis condition was accompanied by lower limb nerve dysfunction had a cognitive or psychiatric disorder coagulation disorders hospitalization data were incomplete.

Design outcomes

Primary

MeasureTime frameDescription
Hemodynamic changeWithin 5 minutes after anesthesiaHeart rate

Secondary

MeasureTime frameDescription
Dose of ephedrine useDuring the surgery periodRecoded dose of ephedrine use

Other

MeasureTime frameDescription
Lower limb functionOne year laterLower limb function (Harris score)
Duration of hospital stayDuring the surgery periodRecoded duration of hospital stay
MortalityPerioperative periodMortality

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026