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Performance of New Diagnostic Methods in Older Adults With Pneumonia

Establishing and Implementing Pneumonia Diagnosis in ED Older Adults: A Mixed Methods Approach

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06092008
Acronym
PNEUMO
Enrollment
250
Registered
2023-10-23
Start date
2022-12-02
Completion date
2027-06-30
Last updated
2026-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia

Brief summary

Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.

Interventions

None listed

Sponsors

Ohio State University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- Adults aged 65 and older presenting to the ED with suspected pneumonia defined as (1) either a physician order for CXR OR CT OR a chief complaint consistent with dyspnea; AND (2) physician suspicion of pneumonia prior to ED testing (score of 2-5 on Likert scale)

Exclusion criteria

* inability to obtain consent from the patient or an LAR * active cancer * organ transplant * immunosuppression * trauma activation * suicidal ideation * incarceration * antibiotics in the last 14 days * a separate episode of lower respiratory illness in the last 30 days

Design outcomes

Primary

MeasureTime frameDescription
Pneumonia3 yearsPresence or absence of pneumonia based on adjudicator review of chart. The goal of the study is to create a diagnostic pathway for pneumonia in older adult emergency department patients.

Countries

United States

Contacts

CONTACTMichael Hill, RN
michael.hill@osumc.edu614-293-6185

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026