Salivary Gland Cancer
Conditions
Brief summary
The INDAGA-UK trial is a retrospective, multi-centre observational study in participants with locally advanced and recurrent salivary gland to investigate t its molecular profiling, and to explore new prognostic and druggable markers. We will analyse samples and data from patients diagnosed with salivary gland cancer from 2013 - 2023. Subject and sample identification will occur over a 12-month period. Samples and data will be analysed over the next 12 months prior to study end.
Interventions
OTHERObservation
Observational study, no intervention
Sponsors
Royal Marsden NHS Foundation Trust
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
1. Aged over 18 2. Histological diagnosis of salivary gland cancer (SGCs) 3. Availability of archival tissue (acceptable after 2013 up to present) 4. Ability to give informed consent (if applicable)\* for retrieving histological specimen and preform molecular analysis \*De-identified archival tissue from deceased patients will be collected as part of the study once REC approval is in place, if the patient was alive when the samples were taken and they are not part of the NHS opt out scheme.
Exclusion criteria
1. Different H&N cancer of other histology 2. Thyroid cancers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| • Description of the molecular and genomic profile of locally advanced and recurrent-metastatic SGCs. | Time Frame: Through study completion, expected duration of 10 years | • Description of the molecular and genomic profile of locally advanced and recurrent-metastatic SGCs. |
Contacts
Primary ContactPablo Jimenez
Backup ContactSarah Burton
Outcome results
None listed