Prosthesis-related Infections
Conditions
Brief summary
The aim of this retrospective observational study is to evaluate the efficacy of antibiotic therapy with dalbavancin in patients presenting with infection on prosthetic devices. The main questions the study aims to answer are: What is the proportion of patients with early discontinuation of dalbavancin therapy? What are the reasons for early discontinuation of antibiotic treatment? What adverse events do patients report? The study is based on data collected as part of routine care practices. Translated with www.DeepL.com/Translator (free version)
Interventions
DRUGDalbavancin Injection
Dalbavancin as long-term suppressive therapy.
Sponsors
Tourcoing Hospital
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with inextricable and/or inoperable osteoarticular or vascular prosthetic material. * Patients requiring suppressive antibiotic therapy (\>6 months) with dalbavancin.
Exclusion criteria
* Patients who are protected adult; * Patients who are minors; * Patients having expressed their opposition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| efficacy of suppressive Dalbavancin therapy | two-year follow-up after initiation of suppressive therapy with Dalbavancin | Proportion of patients successfully treated with Dalbavancin. The efficacy of suppressive therapy will be defined over a two-year period after initiation of treatment as the combination of the following criteria: Clinical control of infection : * Absence of local inflammatory signs (erythema, discharge, edema, pain) ; * Absence of general signs (hyperthermia: T°\>38 or hypothermia T°\< 36°); Biological control: o CRP negative (\<5mg/l) ; |
Countries
France
Outcome results
None listed