Evaluation of Hemodynamic and Ventilatory Effects of Negative Pressure Ventilation

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06088966

Enrollment

Registered

2023-10-18

Start date

2023-08-01

Completion date

2024-04-01

Last updated

2023-10-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Output, Low

Brief summary

Investigation of the effects of negative pressure ventilation after cardiac surgery in adults onto performance of the left and right heart and the lungs.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* patients with pulmonary artery catheter after cardiac surgery

Exclusion criteria

* minimally invasive surgery * unstable conditions * bleeding * unability to fit cuirass

Design outcomes

Primary

Measure	Time frame
Stroke Volume Index in ml/m2	1 hour

Secondary

Measure	Time frame	Description
blood pressure in mm/Hg	1 hour	—
arterial oxygen saturation in %	1 hour	—
mixed venous oxygen saturation in %	1 hour	measured via pulmonary catheter
right ventricular ejection fraction in %	1 hour	measured via pulmonary catheter
Heart rate in beats/min	1 hour	—
Cardiac index in l/min/m2	1 hour	measured via pulmonary catheter
tricuspid annular plane systolic excursion in mm	1 hour	measured via transesophageal echocardiography
right ventricular fractional area change in %	1 hour	measured via transesophageal echocardiography
Vena contract of tricuspid valve in mm	1 hour	measured via transesophageal echocardiography
end diastolic volume index in ml/m2	1 hour	measured via pulmonary catheter

Countries

Germany

Contacts

Primary ContactMatthias Heringlake, Prof. Dr.

anaesthesie.karlsburg@klinikumkarlsburg.de004938355700

Outcome results