Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section

Analgesic Efficacy of Erector Spinae Block , Quadratus Lumborum Block, and Intrathecal Morphine for Postoperative Pain Relief After Cesarean Section: A Randomized Study

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06088420

Enrollment

120

Registered

2023-10-18

Start date

2023-10-15

Completion date

2025-04-05

Last updated

2025-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Pain

Brief summary

comparing analgesic efficacy of different nerve blocks on post operative cesarean sections.

Detailed description

Analgesic efficacy of Erector Spinae, Quadratus Lumborum and Intrathecal Morphine for post operative pain relief after cesarean section,

Interventions

PROCEDUREIntrathcal Morphine Group

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs(10-12 mg 0.5% hyperbaric bupivacaine)

PROCEDUREQuadratus Lumborum nerve block(QL) group

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral QL block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

PROCEDUREErector Spinae nerve block (ESP)group

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral ESP block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* 18-40 years old * more or equal 37 weeks of gestation * ASA 1,2 * Elective cesarean delivery

Exclusion criteria

* Patient refusal * inability to cooperate with or understand the study * local infection. * bleeding disorder * known anaphylaxis to any drug used in the trial * ASA physical status more than 2 * emergency operations * chronic opioid use (opioid use in the past 3 months) * Neurologic deficit or disorder * contraindication to regional anesthesia.

Design outcomes

Primary

Measure	Time frame	Description
Duration of analgesia until first analgesic request.	24 hours .	the time interval from immediate postoperative period until NRS reached 4

Countries

Egypt

Contacts

Primary ContactGhada Abo Elfadl, MD

ghadafadl77@gmail.com01005802086

Backup ContactGhada Abo Elfadl