Skip to content

EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

EXERT-C: Prospective Study of an EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06083324
Acronym
EXERT-C
Enrollment
100
Registered
2023-10-16
Start date
2023-02-03
Completion date
2028-01-16
Last updated
2026-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Keywords

exercise, resistance training

Brief summary

This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.

Interventions

OTHERDose escalated resistance training

All individuals will be engaging in resistance training during and/or after their cancer treatment

Sponsors

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 89 Years
Healthy volunteers
No

Inclusion criteria

1. Age 20-89 years 2. Women of child-bearing potential must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate contraception during the course of the study. 3. Participants must be determined capable of engaging in resistance training by exercise personnel and/or study PI 4. Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel. 5. Individuals not deemed safe to participate in the standard EOC exercise program will be referred to physical therapy or elsewhere

Exclusion criteria

1\. Severe arthritic, joint, cardiovascular, or musculoskeletal condition that would interfere with exercise program

Design outcomes

Primary

MeasureTime frameDescription
Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis3 monthsMeasurement on bioimpedance analysis machine (Inbody 970)
Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound3 monthsMeasurement via ultrasound and calculation with Jackson-Pollack calculations
Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen3 monthsMeasurement on bioimpedance analysis machine (Inbody 970)

Secondary

MeasureTime frameDescription
Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen3 monthsDetermine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen
Determine changes in Y-balance score for each leg3 monthsY-balance score adds up the distance each leg can move in the front and side directions, divided by the length of the hip. This correlates inversely with fall risk.
Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen3 monthsLoad is calculated by multiplying sets by repetitions by weight lifted for a specific exercise
Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen3 monthsEQ-5D asks 5 questions rates from 1-5 and an overall rating of health

Countries

United States

Contacts

CONTACTSamantha Campbell
samantha.campbell@ahn.org(412) 330-6151

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 9, 2026