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B-lines Score as Indicator for the Systemic Volumetric Load During TURP

B-lines Score Derived From Lung Ultrasonography as a Noninvasive Indicator for the Systemic Volumetric Load During TURP. A Prospective Observational Study.

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06079177
Enrollment
125
Registered
2023-10-12
Start date
2024-03-01
Completion date
2024-12-30
Last updated
2024-01-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transurethral Resection of Prostate

Keywords

Lung Ultrasonography score (LUS), extravascular lung water (EVLW), Transurethral resection of the prostate (TURP)

Brief summary

Lung Ultrasonography score (LUS) using B-lines is a noninvasive, reliable and promising method for determining the extravascular lung water (EVLW). This was previously evaluated by trans-pulmonary thermodilution technique. The transurethral resection of the prostate syndrome (TURP-S) is a potentially life-threatening complication of the TURP surgery and timely diagnosis of TURP-S is crucial for rapid detection and optimized treatment. This observational study is designed to investigate the use of LUS using B-lines as a bed-side, simple, and non-invasive indicator for predication of the presence of systemic volume overload in patients undergoing endoscopic TURP.

Interventions

DEVICEUltrasound

LUS using B-lines Caval-Aorta index using ultrasound

Sponsors

Kasr El Aini Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
60 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* Age ≥ 60 years. * American Society of Anesthesiologists Classification (ASA ) I, II, and III. * Full conscious patients.

Exclusion criteria

* Patient refusal. * Who known allergic or hypersensitivity to any drug used in the study (local anesthesia). * Coagulopathy (history of bleeding disorders), or patients on anticoagulant drugs, with (platelets \<50,000 International Normalised Ratio( INR)\>1.5). * Patients have renal dysfunction patients with creatinine ≥ 2. * Patients have uncontrolled cardiac diseases (IHD, (congestive heart failure (CHF), pulmonary hypertension and valvular diseases). * Abdominal ascites. * Patients with local infection at the site of local anesthetic injection. * Failed spinal anesthesia. * Timing not exceed 90 min. * Any patient with lung ultrasound examination at T 0 ≥ 3 B-lines will be excluded from the study.

Design outcomes

Primary

MeasureTime frameDescription
Predictive ability of the LUS using B-lines for the presence of systemic volume overload in patients undergoing endoscopic TURPFrom the preoperative period (T0) to 60 Minutes postoperative (T PACU)using ultrasound

Secondary

MeasureTime frameDescription
Predictive ability of the Caval-Aorta index as predictors of systemic volume overload in patients undergoing endoscopic TURP.From the preoperative period (T0) to 60 Minutes postoperative (T PACU)using ultrasound
Correlation between the absolute value of LUS, Caval-Aorta index .From the preoperative period (T0) to 60 Minutes postoperative (T PACU)using ultrasound
Correlation between the relative changes of the LUS and Caval-Aorta indexFrom the preoperative period (T0) to 60 Minutes postoperative (T PACU)using ultrasound

Countries

Egypt

Contacts

Primary ContactDalia Saad, assi prof
dalia_saad@kasralainy.edu.eg01223911524
Backup ContactAbeer Ahmed, professor
abeer_ahmed@kasralainy.edu.eg

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026