Endovascular Treatment for AIS in Chinese Municipal and County Hospitals： A Real World Study-ETERNITY Registry

Endovascular Treatment for Acute Ischemic Stroke in Chinese Municipal and County Hospitals： A Real World Study-ETERNITY Registry

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06078917

Enrollment

1196

Registered

2023-10-12

Start date

2021-11-01

Completion date

2023-07-31

Last updated

2023-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endovascular Treatment

Keywords

Endovascular Treatment, acute ischemic stroke

Brief summary

To investigate the Endovascular Treatment difference between Chinese city and country hospital.

Detailed description

Endovascular Treatment for AIS in Chinese Municipal and County Hospitals： A Real World Study-ETERNITY Registry is an academic , independent, pragmatic , prospective , multicenter , observational registry study . Patients with acute ischemic stroke caused by anterior circulation intracranial large vessel occlusion and receiving EVT were included. Patients were divided into primary stroke center (county hospital) and senior stroke center (city hospital) groups. Acute ischemic stroke (AIS) workflow, EVT procedural details and clinical outcome were compared in two groups. The aim of the study was to explore the EVT difference in Chinese city and county hospital.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

(1) age ≥18 years; (2) diagnosis of AIS caused by imaging-confirmed intracranial LVO, including isolated cervical internal carotid artery or tandem occlusion, intracranial internal carotid artery, middle cerebral artery (M1/M2), anterior cerebral artery (A1/A2); (3) initiation of any type of EVT, including mechanical thrombectomy, emergent angioplasty via balloon or/and stent; (4).Onset-to-presentation time with 24 hours; (5).Patients whose onset-to-presentation time surpass 6 hours should had CTP and fulfill with DAWN\[6\] or DEFUSE's\[7\] criteria.

Exclusion criteria

(1) Without follow up outcome; (2) posterior circulation stroke;(3)no evidence of LVO on angiogram.

Design outcomes

Primary

Measure	Time frame	Description
The modified Rankin Scale score at 90 days	90 days	The range of the modified Rankin Scale is from 0 to 6. A higher score indicates a worse outcome. 0-No symptoms; 1-No significant disability; 2-Slight disability; 3-Moderate disability; 4-Moderately severe disability; 5-Severe disability; 6-Dead.
Baseline CT/magnetic resonance and CT angiography/magnetic resonance angiography imaging, digital subtraction angiography	90 days	Radiological assessment included ASPECTS ，location of occlusion site, presence of underlying ICAS ，or exist microcatheter First-Pass Effect.
Successful reperfusion	90 days	Successful reperfusion was defined as eTICI ≥2b

Countries

China

Outcome results