HIV Infections
Conditions
Brief summary
The purpose of this study is to determine whether Motivating Youth to Reduce Infections, Disconnections, and Emotion dysregulation (MY-RIDE) decreases substance use , to determine whether MY-RIDE increases human immunodeficiency virus (HIV) prevention strategies and to evaluate MY-RIDE effects on willingness to take Pre-Exposure Prophylaxis (PrEP), stress, substance use urge, and use of mental health and substance use services when compared to attention control youth
Interventions
BEHAVIORALAttention-control group
Participants will receive a one-hour general health promotion session from a nurse and be issued a phone that will deploy the EMA on the same schedule as the intervention arm. They will also receive usual care from the clinics, drop-in center, and shelter recruitment sites. Usual care includes accessing social workers and case managers for immediate housing, food, and clothing needs and assistance in navigating the local Continuum of Care system to access social services.
BEHAVIORALMY-RIDE group
MY-RIDE has three main components: 1) One nurse-led face-to-face session; 2) three months of Ecological Momentary Assessments (EMA) with personalized messaging delivered by phone in real-time in response to one's current risk; and 3) access to on-demand healthcare/PrEP navigation and referrals.
Sponsors
The University of Texas Health Science Center, Houston
National Institute of Nursing Research (NINR)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
* have engaged in substance use (alcohol or illicit drugs) * speak English * are experiencing homelessness * engaged in sexual activity in the last 6 months or plan to in the next month * are not planning to move out of the metro area during the 15-month study period.
Exclusion criteria
* Youth Experiencing Homelessness (YEH) who have low literacy based on the Rapid Estimate of Adult Literacy in Medicine-Short Form (scores \< 4)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in substance use | baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in condom use | baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention | — |
| Change in PrEP uptake as assessed by the self reported tool | baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention | PrEP uptake is defined as the self initiation of HIV prevention medication |
| Change in sexually transmitted infections (STIs) | baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention | This will be assessed by a blood test to detect biomarkers for HIV and Syphilis, and urine test for Gonorrhea and Chlamydia |
Countries
United States
Contacts
CONTACTDiane M Santa Maria, DrPH, MSN, RN, PHNA-BC, FSAHM
CONTACTJennifer Jones
PRINCIPAL_INVESTIGATORDiane M Santa Maria, DrPH, MSN, RN, PHNA-BC, FSAHM
The University of Texas Health Science Center, Houston
Outcome results
None listed