Sickle Cell Disease
Conditions
Keywords
physical therapy, neuromotor performance, functional capacity
Brief summary
The Sickle Cell Children's Exercise Study (SuCCESs) will explore the feasibility and effects of a moderate intensity strengthening, balance, speed, and agility intervention program in children with sickle cell disease.
Detailed description
Participants will perform the baseline assessment and after six weeks of performing the SuCCESs program the participants will perform a post-intervention assessment. Participants will be asked to attend a total of six physical therapy in-person sessions (1x/week) at the University of Maryland Department of Physical Therapy and Rehabilitation Science and to perform 12 home program sessions.
Interventions
BEHAVIORALSuCCESs
strengthening and endurance exercises
Sponsors
University of Maryland, Baltimore
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Masking description
One physical therapist will perform the pre- and post-test assessment measures and another pediatric physical therapist will perform the intervention sessions.
Intervention model description
feasibility study
Eligibility
Sex/Gender
ALL
Age
6 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* Children 6-17 years of age diagnosed with sickle cell disease
Exclusion criteria
* Diagnosis of neurological disorder, not related to sickle cell disease * Lower extremity injury such as a fracture with a cast
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| knee extension strength | week 1 and week 7 | dynamometry to measure knee extension strength |
| Rate of Muscle Activation | week 1 and week 7 | Electromyography used to measure rate of muscle activation |
| exercise tolerance | week 1 and week 7 | 6-Minute Walk Test used to measure exercise tolerance |
| locomotor efficiency | week 1 and week 7 | oxygen uptake used to measure locomotor efficiency |
| number of sessions attended | throughout the entire study week 1, weeks 2-6, six weeks of intervention, and week 7 | attendance |
Countries
United States
Outcome results
None listed