Cognitive Decline, Osteoarthritis
Conditions
Keywords
dementia, lifestyle, multidisciplinary, physical activity, nutrition, depression, anxiety, pain, osteoarthritis, cognitive decline
Brief summary
The goal of this pilot randomised clinical trial is to compare a 12-week Healthy Body & Mind Program to usual care in older adults living with cognitive decline and osteoarthritis. The main questions it aims to answer are: * Does the Healthy Body & Mind Program improve health-related quality of life in older adults living with cognitive decline and osteoarthritis (pre/post and intervention/control)? * Does the Healthy Body & Mind Program improve other health outcomes (cognition, pain, anxiety/depression, physical function) in older adults living with cognitive decline and osteoarthritis (pre/post and intervention/control)? Participants will complete a co-designed and multidisciplinary 12-week program that includes physical activity and lifestyle education (nutrition, social activity and managing anxiety/depression). Researchers will compare outcomes between the intervention group and a wait-list control to see if there are difference in outcome measures (quality of life, cognition, pain, anxiety/depression, physical function).
Interventions
OTHERHealthy Body & Mind Program
12-week physical activity and lifestyle education program
Sponsors
The University of New South Wales
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
The researcher collecting the outcome measures will not know whether the person is in the intervention or control group.
Intervention model description
A randomised trial with a wait-list control.
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults aged 55 or above. * Montreal Cognitive Assessment score 18-25 indicating mild cognitive decline or mild dementia. * Diagnosed with osteoarthritis. * Able to safely undertake study assessments and complete exercise without assistance.
Exclusion criteria
* Montreal Cognitive Assessment score below 18. * Display an abnormal cardiovascular response to exercise (as seen during the baseline exercise test) and your doctor does not provide medical clearance to exercise. * Are unable to speak English and do not have a translator. * Have orthopedic or neuromuscular limitations that prevent you from performing the exercise. * Are deemed unsuitable for group exercise sessions following initial assessment by an Accredited Exercise Physiologist within the UNSW Lifestyle Clinic.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Health-related quality of life questionnaire | 12 weeks | EuroQoL health-related quality of life (EQ-5D; https://euroqol.org/); Score range 0-1; 1 indicating full health, 0 indicating bad health. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cognition questionnaire | 12 weeks | Montreal Cognitive Assessment (MoCA); Score range 0-30; higher scores mean better cognition. Measure can also be broken down into subscales. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Physical function: 6-minute walk test | 12 weeks | Assesses distance in metres walked over 6 minutes as a sub-maximal test of aerobic capacity/endurance. Higher number of metres walked means better physical function and aerobic capacity. |
| Cardiovascular disease (CVD) risk profile questionnaire | 12 weeks | ADCVD (https://tools.acc.org/ascvd-risk-estimator-plus/#!/calculate/estimate/). Tool calculated % risk, higher % indicates greater risk for CVD. |
| Chronic pain questionnaire | 12 weeks | Western Ontario and McMaster Universities Arthritis Index (WOMAC); Score range 0-96; 0 represents best health, higher scores indicate more pain. Measure can also be broken down into subscales (e.g., pain and function). |
| Physical function: handgrip strength physical test | 12 weeks | Accesses physical strength in kilograms (kg). Average score of 3 attempts on each hand using a dynamometer; higher kg indicates more strength. |
| Physical function: single leg stance test (balance) physical test | 12 weeks | Physical test used to assess static postural and balance control. The participant must stand unassisted on one leg and is timed in seconds from the time one foot is flexed off the floor to the time when it touches the ground or the standing leg or an arm leaves the hips. Higher number of seconds indicates better balance. |
| Sleep questionnaire | 12 weeks | Pittsburgh Sleep Quality Index (PSQI); Score range 0-21; higher scores indicate worse sleep) |
| Depression, anxiety & stress questionnaire | 12 weeks | Depression Anxiety Stress Scales (DASS-21); Score range 0-21; higher scores mean worse psychological health. Measure can also be broken down into subscales: depression, anxiety & stress. |
Countries
Australia
Contacts
Primary ContactClaire Burley, PhD
Backup ContactBelinda Parmenter, PhD
Outcome results
None listed