Weight Loss Following an Episode of Pre-eclampsia Using a Dissociated or Hypocaloric Diet in Overweight or Obese Patients

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06067906

Acronym

POPADIPE

Enrollment

Registered

2023-10-05

Start date

2023-11-02

Completion date

2028-11-02

Last updated

2024-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-Eclampsia, Obesity

Keywords

pre-eclampsia, obesity, dissociated diet

Brief summary

In view of the known link between pre-eclampsia, overweight/obesity and chronic kidney disease, the aim is to offer for obese and overweight patients to reduce their BMI without reducing lean body mass. The POPADIPE project will make it possible to limit overweight or obesity by means of nutritional management chosen by the patient (hypocaloric or a dissociated diet). The latter has been the subject of little scientific investigation, particularly in relation to the management of post-pre-eclampsia.

Interventions

OTHERHypocaloric diet

Hypocaloric diet

OTHERDissociated diet

Dissociated diet

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Person affiliated to social security * Free, informed and written consent signed by the participant and the investigator (no later than the day of day of inclusion and before any examination required by the research) * Patient over 18 years of age at the time of inclusion and \< 45 years of age * Having had an pre-eclampsia in the last 5 years according to the definitions of the ISSHP 2018 * Patient with a BMI between 25 kg/m² and 40 kg/m² who accepts dietetic follow up * Patient with a medical prescription for dietetic follow-up aimed at losing weight loss * Patient with a balanced diet

Exclusion criteria

* Patients with a mental disability or language barrier that prevents them from understanding or consenting to the study * Patients deprived of their liberty by judicial or administrative decision * Patients under psychiatric care * Patients subject to a legal protection measure * Patients with cognitive disorders or defined eating disorders * Patients who are pregnant or breast-feeding * Patients undergoing steroid treatment and/or immunosuppression * Have been on a low-calorie or dissociated diet for at least 6 months * Patients with CKD stage ≥ 3A

Design outcomes

Primary

Measure	Time frame	Description
Demonstrate Efficiency of personalised dietary management on weight loss in patients with a history of pre-eclampsia	1 year after care	Efficiency is evaluated by weight measurement

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026