Perioperative Analgesia in Neonates
Conditions
Keywords
perioperative analgesia, primary cleft lip repair surgery, infraorbital peripheral blockade
Brief summary
In retrospective data search the investigators will identified the cumulative consumption of opioid analgesics during surgery and 24 hours after surgery in neonate with cleft lips who underwent primary cleft lip repair surgery.
Detailed description
The cumulative consumption of opioids during surgery and 24 hours after surgery in neonates with cleft lips who underwent primary cleft lip repair surgery is not known. Patients were divided into two groups according to the time period when they underwent surgery. Group 1 were neonates who underwent primary cleft lip repair surgery under general anaesthesia without regional anaesthesia - the time period before regional anesthesia is introduced into the standard procedure. Group 2 are newborns who underwent primary cleft lip repair surgery under general anaesthesia with regional anaesthesia. Group 1 underwent surgery in time period before regional anesthesia was introduced into the standard procedure. In this retrospective study, the anesthesiology perioperative data from January 2018 till December 2021 in the tertiary center of Pediatric anaesthesia will be evaluated.
Interventions
PROCEDUREthe standard procedure - without regional anaesthesia
the standard procedure - without regional anaesthesia
PROCEDUREinfraorbital peripheral blockade with or without nasal peripheral blockade according to the preference of the anesthesiologist and surgeon
infraorbital peripheral blockade with or without nasal peripheral blockade according to the preference of the anesthesiologist and surgeon
Sponsors
Masaryk University
Brno University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Days to 28 Days
Healthy volunteers
No
Inclusion criteria
* neonates with unilateral or bilateral cleft lip (U/BCL), all neonates with unilateral or bilateral cleft lip and alveolus (U/BCLA) or with unilateral or bilateral cleft lip, alveolus and palate (total cleft; U/BCLAP) who underwent cleft lip repair surgery in the neonatal period * the study period (1/2018-12/2021)
Exclusion criteria
* ● presence of coagulopathy * thrombocytopenia or thrombopathy * patients at risk of malignant hyperthermia * patients who were not neonates (older than 28 days) * patients who required postoperative mechanical ventilation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The cumulative consumption of opioids during surgery and 24 hours after surgery | 24 hours after surgery | The cumulative consumption of opioid analgesics during surgery and 24 hours after surgery in neonates with regional block compared to neonates without regional anesthesia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Oral intake | 24 hours after surgery | Difference in time of first oral intake after surgery in the group with regional anesthesia compared to with the group without regional anaesthesia |
| Complications | 24 hours after surgery | Complications of regional anesthesia including suction disorders in the group with regional anaesthesia |
Countries
Czechia
Outcome results
None listed