Metabolic Disorders, Obese, Overweight, Postpartum
Conditions
Keywords
Wellness/Behavior Change
Brief summary
The goal of PrepareD is to examine whether the prepregnancy weight-loss intervention administered during the Prepare trial \[NCT02346162\] has an influence in the postnatal period. PrepareD is a cohort study (no intervention) that will address new specific aims through one in-person visit with mothers and children, dietary recalls, actigraphy, and the use of medical record weights. The goal is to collect data when the child is 3 years old. However, due to the COVID-19 pandemic, the investigators expanded the data collection window in order to collect data up to when the child is 5 years old. The investigators hypothesize that intervening on women before pregnancy is the key to breaking the multigenerational cycle of obesity.
Interventions
None listed
Sponsors
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Penn State University
Kaiser Permanente
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* Mother must be a Prepare \[NCT02346162\] participant who has experienced a viable pregnancy during the Prepare trial * Child must be the first viable offspring born to a Prepare participant after consent into the Prepare study
Exclusion criteria
None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mother postpartum weight retention (PPWR) in pounds at 5 weeks and 1 year postpartum | 5 weeks and 1 year after delivery | All weights recorded for the mother in the EMR between delivery and up to 5 weeks and 1 year postpartum will be collected. PPWR at 5 weeks and 1 year after delivery will be obtained by subtracting mother's 5-week postpartum weight (in lbs) and 1-year postpartum weight (in lbs) from mother's weight (in lbs) at delivery, respectively. |
| Child body mass index (BMI) from birth up to 5 years of age | Birth up to 5 years of age | All child weights, lengths (before age 2), and heights (after age 2) recorded in the electronic medical record (EMR) between delivery and up to 5 years of age will be collected. Child weight and height between 3 years 0 months of age up until 5 years of age will be measured at an in-person research visit. Weight in kilograms (kg) and height in meters (m) will be combined to report BMI in kg/m\^2. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Healthy Eating Index (HEI) score for mother and child | At study visit, when child is 3-4 years of age | Mother and child dietary data will be collected via dietary recalls following the study visit in order to calculate HEI total and component scores for mother and child. |
| Daily activity level for mother and child | At study visit, when child is 3-4 years of age | Mother and child activity level will be collected via actigraphy. |
Countries
United States
Outcome results
None listed