Intubation Complication
Conditions
Brief summary
Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia
Detailed description
Comparing hemodynamic profile of patients during induction of General Anesthesia with intravenous morphine as an adjuvant drug versus Intravenous esmolol as an adjuvant agent,My aim is to study which drug has superior hemodynamic profile in terms of hemodynamic stability of patient requiring General Anesthesia.
Interventions
Morphine group(an opioid), participants were given intravenous morphine(an opioid) at induction of General Anaesthesia before laryngoscopy and intubation. The other group,Esmolol group(cardioselective beta blocker), participants were given intravenous esmolol(cardioselective beta blocker) during induction of General Anesthesia before laryngoscopy and intubation.
Sponsors
Pakistan Navy Station Shifa Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* ASA 2 patients presenting for elective surgery.
Exclusion criteria
* Patients having major cardiac disease. * Metastatic disease. * Pregnant females. * Those unwilling to be part of study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure | 06 months | Change in blood pressure between baseline value and post Intubation value will be measured in millimeter of mercury (mmHg). |
| Pulse rate | 06 months | Change in pulse rate between baseline value and post intubation value will be measured per minute. |
Countries
Pakistan
Outcome results
None listed