Prevalence and Incidence of Multiple Revisions Following Knee Arthroplasty in Denmark 1998-2021: A Nationwide Population-based Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06064318

Acronym

EMKAR ONE

Enrollment

161384

Registered

2023-10-03

Start date

2023-02-01

Completion date

2024-04-01

Last updated

2025-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Replacement, Knee Replacement Revision

Brief summary

The purpose of this study is to investigate the incidence and prevalence rates of multiply revised knee arthroplasty patients in Denmark from 1998-2021.

Interventions

PROCEDURERevision

Any type of knee revision, excluding knee arthrodesis and femur amputation

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Danish Resident * all ages * must have had primary knee arthroplasty procedure performed in Denmark between 1998-2021

Exclusion criteria

* Missing key variables (patient ID, date of surgery, procedure-code, laterality of procedure) * Duplicates * Non-relevant procedures

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of major n-grade revisions	23 years	standardized prevalence of major n-grade revisions
Incidence of major n-grade revisions	23 years	standardized incidence of major n-grade revisions
Prevalence of all n-grade revisions	23 years	standardized prevalence of all n-grade revisions
Incidence of all n-grade revisions	23 years	standardized incidence of all n-grade revisions

Secondary

Measure	Time frame	Description
Prevalence of major and all n-grade revisions stratified by sex and age	23 years	Calculation of prevalence for major and for all n-grade revisions stratified by sex and by age (groups, sex: male/female, age: 18-49/50-69/70-99)
Prevalence of major and all n-grade revisions for patients with their total sum of revisions	23 Years	Calculation of standardized prevalence for patients receiving major or all type of n-grade revision, where the ordering of revisions are not knee specific but patient-specific
Incidence of major and all n-grade revisions stratified by sex and age	23 years	Calculation of incidence for major and for all n-grade revisions stratified by sex and by age (groups, sex: male/female, age: 18-49/50-69/70-99)

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026