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Maximal Rate of Force Development of Ankle Muscles and Functional Ability in Patients With Knee Osteoarthritis

Assessment of Maximal Rate of Force Development of Ankle Muscles and Its Association Functional Ability in Patients With Knee Osteoarthritis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06063889
Enrollment
126
Registered
2023-10-03
Start date
2023-07-20
Completion date
2024-02-02
Last updated
2024-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthritis, Knee Osteoarthritis

Brief summary

This study is a detailed assessment of the maximal rate of force development of ankle muscles and its association with functional ability in patients with knee osteoarthritis (OA).

Detailed description

This research is designed to study the link between force development in ankle muscles and functional abilities in knee OA patients. It aims to understand the influence of ankle muscle strength, specifically plantar flexors, on the stability, pain, and functionality of patients with knee OA. The study will analyze the rate of force development, its importance in explosive strength improvement, and impact on preventing knee injuries. Furthermore, it will investigate the compensatory mechanism of the plantar flexors developed by patients in advanced stages to balance other muscle failures.

Interventions

DIAGNOSTIC_TESTMaximal Rate of Force Development Test for Ankle Muscles

This test is designed to measure the maximal rate of force development in the ankle muscles, specifically the plantar flexors. It aims to assess the relationship between the strength of these muscles and the functional ability in patients with knee osteoarthritis. The results from this test will help to understand how lower limb muscle strength influences the symptoms and progression of knee osteoarthritis.

Sponsors

Ahram Canadian University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
30 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Group 1 (Knee OA group) 1. Patients diagnosed with knee osteoarthritis according to Performance of the 2018 classification criteria for early stage knee OA was tested using data from the Osteoarthritis Initiative (OAI (Leung et al.,2020). 2. Grade 2-3 KOA cases according to Kelgren-Lawrance classification 3. Having knee pain for at least 6 months. 4. The visual analog scale (VAS) score being at least 3 or more. * Group 2 (Healthy control group) 1. Individuals with no signs or symptoms of Knee OA or other neurological or musculoskeletal conditions.

Exclusion criteria

1. Patellar subluxation 2. Surgery in any joint of the lower limb 3. Meniscal injury 4. Ligament instability 5. Patients who received intra-articular injection in the knee in the last 6 months 6. Patients with problems in the hip and ankle 7. Patients who participated in in another physical therapy program in the last 3 months were not included in the study.

Design outcomes

Primary

MeasureTime frameDescription
Knee Osteoarthritis Outcome Score (KOOS)BaselineThe KOOS is a questionnaire that assesses five aspects of knee injury and osteoarthritis: pain, symptoms, ADL function, sport and recreation function, and quality of life. Scores are transformed to a 0-100 scale, with zero representing extreme knee problems and 100 representing no knee problems. Higher scores indicate better function and less pain.
Forward Step Down Test (FSDT)BaselineThis functional ability test requires participants to perform as many repetitions as possible in 30 seconds of a specific movement. The number of valid repetitions performed in this duration is recorded.
Single Leg Hop Test (SLHT)Baselinen this test, participants hop forward as far as possible on one leg, and the distance hopped is recorded.
Isokinetic Testing ProceduresBaselineThis procedure involves conducting tests of three (60°/s) or five (120°/s) maximal nonconsecutive efforts with specific rest intervals. Each subject is instructed to exert maximal effort throughout the whole range of motion.
Rate of Force Development (RFD)BaselineThe RFD is a measure of the speed at which the force of a muscle contraction develops. It is typically measured during isometric contractions and provides information about the muscle's explosive strength capacity.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026