Multiple Sclerosis, Parkinson Disease, Stroke
Conditions
Keywords
dexterity, training
Brief summary
Primary objective of this study is to explore the impact of a 3-week upper limb hand function training in patients with PD, MS or stroke. The benefits on hand function of this training program will be evaluated. The hypothesize is that the 3-week upper limb hand function training improves finger dexterity.
Detailed description
Patients with Parkinson's disease (PD), multiple sclerosis (MS) or stroke often suffer from significantly decreased coordination and have difficulties with precise hand/finger movements during the performance of both basic activities of daily living (ADL), such as dressing, grooming as well as higher ADL, such as cooking, shopping and regular medication intake. The investigators explore the effects of a new, interactive, sensor-home-based upper limb hand training on upper limb related ADL in patients with PD, MS or stroke.
Interventions
DEVICEsmart sensor egg training
The portable hand trainer has three principal functionalities: (I) Grasping, (II) Pronosupination, and (III) wrist and finger extension. Different exercises can be done.
Sponsors
Luzerner Kantonsspital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
sensor-home-based hand training for MS, PD, stroke or control group
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with confirmed PD, according to UK Brain bank Criteria (Hughes et al., 1992) or * MS patients with relapsing-remitting MS (RRMS), secondary-progressive MS (SPMS) or primary progressive MS (PPMS) according to the revised McDonald's criteria or * subacute stroke * written and signed informed consent * self-reported hand function problems or * healthy subject * written and signed informed consent * no self-reported hand function problems
Exclusion criteria
* MoCA \<21/30 * psychiatric disease * participation on other interventional trials * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| hand dexterity | 3 weeks | Nine Hole Peg test (9-HPT): The 9-HPT is a standardized, well established, and reliable measure of hand dexterity in patients with PD, MS, or stroke. seconds will be measured. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| grip strength | 3 weeks | The handheld JAMAR dynamometer measures the grip strength. kg will be measured. |
| cognition | baseline | Montreal Cognitive Assessment (MOCA): Cognitive screening tool with a scale from 0 - 30 points. A higher score means a better outcome. |
| executive function | 3 weeks | Trail Making Tests (TMT) parts A & B. Results for both TMT A and B are reported as the number of seconds required to complete the task; therefore, higher scores reveal greater impairment. |
| fine finger movements | 3 weeks | Coin rotation task (CRT): The CRT measures fine coordinated finger movements and is a suitable and valid dexterity test in patients with PD, MS, or stroke. The seconds for 20 halfturns will be measured. |
| self-reported arm and hand function related problems in patients with MS | 3 weeks | Patients with MS: The Arm Function in Multiple Sclerosis Questionnaire (AMSQ): This questionnaire is a standardized patient self-rated outcome measure (PROM) for evaluating arm and hand function in patients with MS. Containing 31 items with a range of 1 - 100 points. Higher scores indicate more limitations in hand and arm function. |
| Arm and hand function in stroke patients | 3 weeks | Patients with stroke: Upper limb limos: Mesures arm and hand function in ADL. |
| self-reported dexterity related problems in daily living for PD | 3 weeks | Patients with PD: Dexterity Questionnaire 24 (DextQ-24): This questionnaire is a standardized patient self-rated outcome measure (PROM) for evaluating dexterity related ADL in PD. score range 24-96, higher scores mean more dexterity problems. |
Countries
Switzerland
Contacts
Primary ContactManuela Pastore, PhD
Backup ContactCornelia Cox
Outcome results
None listed