Effects of Multimodal Physical Therapy in Patients With Lumbosacral Radiculopathy

Effects of Multimodal Physical Therapy on Pain, Disability, H-reflex, and Diffusion Tensor Imaging Parameters in Patients With Lumbosacral Radiculopathy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06058806

Enrollment

Registered

2023-09-28

Start date

2018-06-01

Completion date

2020-01-20

Last updated

2023-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbosacral Radiculopathy

Keywords

Lumbosacral Radiculopathy, Lumbar disc herniation

Brief summary

Purposes of the study To investigate the effect of Multimodal Physical Therapy on pain, daiablility H-reflex, and Diffusion Tensor Imaging (DTI) Parameters in Patients With Lumbosacral Radiculopathy.

Detailed description

Participants will receive Multimodal Physical Therapy program consisting of electrophysical agents, manual therapy interventions, and core stability exercises. Patients will receive the intervention for six weeks. Outcomes will be assessed at baseline and post-intervention.

Interventions

OTHERMultimodal Physical Therapy

Multimodal Physical Therapy program consisting of electrophysical agents, manual therapy interventions, and core stability exercises

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 45 Years

Healthy volunteers

Inclusion criteria

* chronic (≥ 3 months) unilateral Lumbosacral Radiculopathy (LSR) * The LSR is due to paracentral L4-L5 or L5-S1 Lumbar disc herniation * The LSR is confirmed radiologically by MRI * The LSR is confirmed clinically by history and physical examination * The LSR is confirmed neurophysiological by soleus H-reflex assessment * Body mass Index less than 30 * 20-45 years of age

Exclusion criteria

* systematic disease * Bilateral symptoms * Lumbar spinal stenosis * previous surgery * Steroid injection * Spinal fracture * Lumbar spinal stenosis * Spinal deformity * Spinal fracture * Radiological evidence of bilateral nerve root encroachmen * Evidence of H-reflex amplitude or latency affection on asymptomatic side

Design outcomes

Primary

Measure	Time frame	Description
Pain	Change from Baseline pain at 6 weaks	Visual analog scale (VAS)
Disability	Change from Baseline Disability at 6 weaks	Roland-Morris Disability Questionnaire (RMDQ)
Soleus H-reflex amplitude	Change from Baseline Soleus H-reflex amplitude at 6 weaks	by EMG unit
Soleus H-reflex side-to-side amplitude (H/H) ratio	Change from Baseline Soleus H/H ratio at 6 weaks	by EMG unit
Fractional anisotropy (FA) of the compressed nerve root	Change from Baseline Fractional anisotropy (FA) ratio at 6 weaks	by MRI examination
Apparent diffusion coefficient (ADC) of the compressed nerve root	Change from Baseline Apparent diffusion coefficient (ADC) at 6 weaks	by MRI examination

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026