Postoperative Pain
Conditions
Brief summary
The patients will be randomly allocated into two equal groups using a computer program. Group A: will receive external oblique intercostal block after induction. Group B: will receive postoperative morphine per patient request.
Detailed description
General anaesthesia induction will be achieved using fentanyl 1µg/kg (IV), propofol 2mg/kg (IV), and0.5mg/kg of IV Atracurium. General anaesthesia will be maintained with mechanical ventilation with isoflurane with O2 \\ Air mixture. During anaesthesia maintenance Intraoperatively, if BP or heart rate (HR) increase more than 20% from baseline, intravenous morphine will be given to stabilize the patients' haemodynamics. All patients will receive 1g intravenous paracetamol and 4mg ondansetron 8mg dexamethasone.
Interventions
PROCEDUREexternal oblique intercostal block
20 ml of bupivacaine 0.25% will be administered by US into external oblique intercostal plane at the level of sixth rib space .
Sponsors
Menoufia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- Eligible patients will be older than 18 years old with American society of anestheologist ASA physical status I, II and III scheduled for Trans-Abdominal ( Anterior Subcostal) Nephrectomy
Exclusion criteria
* Patients who are: * Unable to cooperate. * Patients who have allergy to any of the study drugs. * Patients who are on opioids. * Known abuse of alcohol or medication. * Local infection at the site of injection or systemic infection. * Pregnancy * Patients with coagulation disorders or on anticoagulation therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time for first rescue analgesia | day 0 | hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| rescue analgesics | 24hous | morphine mg |
| VAS score | 24 hours | 1 to 10 (0 is interpreted as no pain, 1-4 mild pain, 5-6 moderate pain, 7-10 severe pain) |
Countries
Egypt
Outcome results
None listed