Compliance, Patient, Medium Flow Anesthesia, Minimal Flow Anesthesia, Peak Inspiratuar Pressure, Pulmonary Function Test
Conditions
Brief summary
The patients were randomized into two groups medium flow anesthesia (MeFA) and minimal flow anesthesia (MiFA). While MeFA received medium flow anesthesia with 2 lt/min, MiFA received minimal flow anesthesia with 0.5 lt/min fresh gas flow. In both groups dynamic compliance values, peak inspiratory pressure (PIP) values, total inhalation anesthetic drug consumption, total remifentanil drug consumption, duration of anesthesia, and duration of surgery were recorded. The FVC, FEV1, and FEV1/FVC values of the patients in both groups were evaluated and noted 24 hours before the operation, after the operation 2nd, 8th, and 24th hours.
Interventions
OTHERMedium flow anesthesia
Group MeFA; after reaching the MAC 1 value with 4lt/min 50% O2 - 50% air and 8% desflurane with remifentanil infusion, medium flow anesthesia was started with 2 lt/min 50% O2 - 50% air with MAC 1 concentration desflurane. The vaporizer was closed at the end of the last suture, and the flow was increased to 80% oxygen at 6 lt/min.
Group MiFA; after reaching the MAC 1 value with 4 lt/min 50% O2 - 50% air and 8% desflurane with remifentanil infusion, minimal flow anesthesia was started with 0.50 lt/min 50% O2 - 50% air with MAC 1 concentration of desflurane. The vaporizer was closed at the end of the last suture, and the flow was increased to 80% oxygen at 6 lt/min.
Sponsors
Ataturk University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* ASA I-II * 18-65 years of age, who will undergo elective laparoscopic cholecystectomy surgery
Exclusion criteria
* ASA III-IV * Smokers * Body mass index (BMI) \> 40 kg / m2, * Patients with cardiovascular system disease * Chronic respiratory diseases, * Patients whose pulmonary function tests cannot be applied and who have problems with pulmonary function tests during the examination of the chest disease consultant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Peak inspiratory pressure assessment | 5th minutes after endotracheal intubation | Peak inspiratory pressure will be assessed 5th minutes after endotracheal intubation |
| Dynamic Compliance assessment | 5th minutes after endotracheal intubation | Dynamic Compliance will be assessed 5th minutes after endotracheal intubation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| FEV1 measures assessment | 24 hours before the operation | FEV1 measures assessment will be assessed 24 hours before the operation |
| FEV1 measures assessmentt | 8th hour after the operation | FEV1 measures assessment will be assessed 8th hours after the operation |
| FVC measures assessment | 24 hours before the operation | FVC measures assessment will be assessed 24 hours before the operation |
| FEV1/FVC measures assessment | 24 hours before the operation | FEV1/FVC measures assessment will be assessed 24 hours before the operation |
Countries
Turkey (Türkiye)
Outcome results
None listed