Predictive Value of Right Atrial Strain in Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06054360

Acronym

ODFAPO

Enrollment

334

Registered

2023-09-26

Start date

2023-10-09

Completion date

2026-10-09

Last updated

2026-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Atrial Fibrillation, Strains

Keywords

coronary bypass grafting, postoperative atrial fibrillation, strain, left atrial, right atrial

Brief summary

The incidence of postoperative atrial fibrillation (POAF) after cardiac surgery is around 30%. POAF increases the risk of developing permanent atrial fibrillation and raises the risk of cardiac decompensation, stroke, acute myocardial infarction, and death. While the role of the left atrium (LAF) in the pathophysiology of POAF is now well-established, the part of the right atrium (RA) remains poorly understood. Recent studies suggest a correlation between RA function and POAF. RA function can be assessed by transthoracic echocardiography (TTE) with dedicated software for measuring the RA strain (RAS). RA function is thus divided into three phases: reservoir (RASr), conduit, and contraction. Numerous studies have demonstrated that a significant alteration in RAS predicts POAF in various clinical contexts. Therefore, it is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery. It is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patient (\>18 years old) * The patient was hospitalized at the Amiens University Hospital for scheduled aortocoronary bypass grafting under cardiopulmonary bypass. * Echocardiographic image quality enabling the measurement of RAS parameters * Patient affiliation to a social security scheme * Patient/proxy information and collection of their non-opposition.

Exclusion criteria

* Patients participating in an interventional study may modify the incidence of POAF. * History of atrial fibrillation or flutter. * Valvular and ascending aorta cardiac surgery * Urgent cardiac surgery. * Presence of tricuspid insufficiency greater than grade 2. * Left ventricular ejection fraction lower than 50%. * Patient receiving circulatory mechanical assistance before surgery. * Dependency on ventricular and atrial pacing by an internal or external cardiac pacemaker during the echocardiographic examination.

Design outcomes

Primary

Measure	Time frame	Description
Correlation of RASr parameter variation with POAF incidence	30 months	Correlation of RASr parameter variation with POAF incidence in patients undergoing postoperative cardiac surgery

Countries

France

Contacts

CONTACTCamille DAUMIN, MD

daumin.camille@chu-amiens.fr03 22 08 77 95

Outcome results