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Risk Factors for Refeeding Syndrome in the Surgical Intensive Care Unit

Risk Factors for Refeeding Syndrome in the Surgical Intensive Care Unit

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06054139
Enrollment
60
Registered
2023-09-26
Start date
2023-06-09
Completion date
2024-07-09
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refeeding Syndrome

Keywords

hypophosphatemia, hypomagnesemia

Brief summary

Refeeding Syndrome is a condition that occurs when patients who are undernourished or undernourished suddenly start overfeeding, causing electrolyte disturbances and vitamin deficiencies, resulting in neurological and cardiac problems. It may even result in death. It is aimed to prevent the development of Refeeding Syndrome with nutrition in accordance with the guidelines. The aim of this study is to determine the risk factors for Refeeding Syndrome in Intensive Care Unit (ICU).

Detailed description

Nutritional support is an important part of treatment in intensive care patients. Especially existing comorbidities and developing acute problems before intensive care admission can cause serious malnutrition for patients. Refeeding syndrome is a serious, life-threatening condition accompanied by electrolyte and metabolic disorders as a result of rapid re-feeding following prolonged starvation or malnutrition. The condition may be accompanied by electrolyte disorders such as hypophosphatemia, hypokalemia and hypomagnesemia, as well as decrease in vitamin levels (especially vitamin B1), fluid imbalance and salt retention. The resulting imbalances can cause cardiac and neurological side effects, impaired organ functions and even death. The refeeding protocol should be individualized to each patient's clinical situation. In this study, although nutritional protocols in accordance with the guidelines are applied in patients with risk factors for the development of Refeeding Syndrome, whether Refeeding Syndrome develops and the facilitating factors will be investigated in ICU.

Interventions

OTHERRefeeding Syndrome

Patients who developed Refeeding Syndrome despite proper nutrition while receiving treatment in the ICU

Sponsors

Samsun University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

1. Patients are intensive care patients 2. Patients' age \> 18 -

Exclusion criteria

1. Diabetic ketoacidosis 2. Other risk factors for hypophosphatemia (patients on continuous hemodialysis, hyperphosphatemia treatment, parathyroidectomy) 3. Patients with pre-study hypophosphatemia (\< 0.65 mmol/L) 4. Patients with hyperparathyroidism 5. Terminal stage cancer patients 6. Patients with Glasgow Coma Scale ≤5 7. Patients with respiratory and metabolic alkalosis -

Design outcomes

Primary

MeasureTime frameDescription
Occurrence of Refeeding Syndromefrom june 9, 2023 to june 9, 2024Occurrence of RFS:Within 72 hours after feeding serum phosphorus \< 0.0.87mmol/L, or from the baseline levels drop \> 0.16% or drop \> 30%;And (or) hypokalemia, hypomagnesemia, hypocalcemia and corresponding clinical symptoms

Countries

Turkey (Türkiye)

Contacts

Primary ContactŞERİFE SEÇGİN
kuvez@hotmail.com+905556166112
Backup ContactDİLAN AKYURT
dilanakyurt@gmail.com+905062344791

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026