Risk Factors And Outcomes Of Hospital Acquired AKI

Risk Factors And Outcomes Of Hospital Acquired Acute Kidney Injury: A Tertiary Health Care Center Experience

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06051708

Enrollment

160

Registered

2023-09-25

Start date

2023-06-01

Completion date

2024-05-15

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AKI - Acute Kidney Injury

Keywords

AKI, Hospital Acquired, risk factors, outcomes

Brief summary

The aim of the study is to assess the common risk factors for development of hospital acquired acute kidney injury among hospitalized patients in Alexandria Main University hospital and their outcomes.

Detailed description

Hospital-acquired AKI (HAAKI) is defined as acute renal insult occurring 48 hours or more after admission to a health care facility and It is estimated to occur in 13-18% of hospitalized patients. The early diagnosis of HAAKI reflects on improvement in morbidity and mortality rates especially in developing countries which goes parallel with the goal The International Society of Nephrology (ISN) to eliminate preventable or treatable deaths from AKI by 2025, the 0 by 25 initiative. Data concerning the spectrum of acute kidney injury (AKI) in Egypt are generally scarce.

Interventions

OTHERstandard AKI care bundle

AKI care bundle include use of iv fluids, diuretics, antihyperkalemic drugs, sodium bicarbonate, antibiotics in septic patients.

OTHERstandard care for hospitalized patients

this includes iv fluids, diuretics, antibiotics in septic patients, other measures according to original disease

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Fulfilment of definition of acute kidney injury according to KDIGO reference. 2. Age more than 18 years.

Exclusion criteria

1. Mentally or physically unfit patients. 2. Patients who developed acute kidney injury within 48 hours of admission to hospital.

Design outcomes

Primary

Measure	Time frame	Description
Recovery of kidney functions	12 weeks	(improvement of eGFR, serum creatinine to normal or previous baseline).

Secondary

Measure	Time frame	Description
progression to chronic kidney disease.	12 weeks	deterioration of kidney functions ( creatinine, eGFR)
mortality	12 weeks	death
Need for renal replacement therapy	12 weeks	different modalities of RRT

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026