Postoperative Pain
Conditions
Keywords
Peritonitis, Postoperative pain, Lidocaine, Burkina Faso
Brief summary
Intravenous administration of lidocaine perioperatively after laparotomy for peritonitis could be an interesting alternative by reducing the duration of postoperative ileus, the intensity of pain and the patient's hospital stay, as well as the cost of management in our context of lack of financial, technical and human resources, hence the present study.
Interventions
DRUGSerum saline intravenous
Perioperative serum saline intravenous administration
DRUGLidocaine intravenous
Perioperative lidocaine intravenous administration
Sponsors
Université NAZI BONI
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Intervention model description
This will be a randomized, double-blind clinical trial conducted at University hospital Charles De Gaulle of Ouagadougou, comparing the results of intravenous administration of lidocaine perioperatively versus administration of saline
Eligibility
Sex/Gender
ALL
Age
6 Years to 15 Years
Healthy volunteers
Yes
Inclusion criteria
* All patients aged 6 to 15, Classified according to the American Society of Anaesthesiologists (ASA) (I, II and III) admitted for peritonitis and whose parents have given informed consent
Exclusion criteria
* State of shock * Severe renal insufficiency (creatinine clearance less than 30 ml/min) * History of allergy to lidocaine * Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Resumption of transit | Up to 7 days during the postoperative period. From the date of randomization to the first postoperative gas and/or the presence of postoperative bowel sounds in the patient | time to first gas and/or presence of bowel sounds |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Analog visual scale | Postoperative pain scores at 24 hours | Average pain score, minimal value is 0, maximal value is 10 and higher score mean worse |
| Concentration of C-reactive protein | Hours 24 postoperative | Average of C-reactive protein |
| Hospitalisation | Up to 30 days during the postoperative period. From the date of randomization to the patient's discharge from hospital or date of death | Number of days in hospital |
| Postoperative mortality | Up to 30 days during the postoperative period. From date of randomization to date of death | Number of postoperative deaths |
Contacts
Primary ContactBertille KI, Doctor
Backup ContactIsmael GUIBLA, Doctor
Outcome results
None listed