Post Operative Pain
Conditions
Brief summary
The patients will be randomly allocated into two equal groups using a computer program. Group A: will receive U S guided external oblique intercostal block after induction. Group B: Patients will receive US guided erector spine block after induction.
Detailed description
Patients will be premedicated with IV midazolam (0.05 mg/kg). Under standard monitoring including Electrocardiography, Non-Invasive Blood Pressure, and Pulse Oximetry. General Anesthesia will be induced with Fentanyl (1-2 μg/kg), Propofol (2-3 mg/kg), and Atracurium (0.5-0.8 mg/kg). Pressure controlled Volume guarantee Ventilation mode will be used to maintain O2 Saturation Above 98%. Anesthesia will be maintained with Isoflurane 1.2 Minimum Alveolar Concentration inhalation
Interventions
PROCEDUREexternal oblique intercostal block
U S guided external oblique intercostal block after induction.
PROCEDUREErector Spine block
US guided erector spine block after induction
Sponsors
Menoufia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Eligible patients will be older than 21 years old with American society of anesthesiology ASA physical status I& II&III scheduled for elective (Subcostal) Nephrectomy
Exclusion criteria
* Patients who are: * Uncooperative. * Having allergy to any of the study drugs. * Known abuse of alcohol or medication. * Having Local infection at the site of injection or systemic infection. * Pregnancy. * With coagulation disorders or on anticoagulation therapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| time for first rescue analgesia | day 0 | hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| visual analogue score VAS score | 24 hours | (a scale from 0 to 10 where 0 is interpreted as no pain, 1-4 mild pain, 5-6 moderate pain, 7-10 severe pain) will be recorded 15 min after extubation (as soon as the patient will be alert enough to report pain) |
| the number of rescue analgesics | 24hours | numbers' |
Countries
Egypt
Outcome results
None listed