Cesarean Section; Infection
Conditions
Keywords
surgical site infection, Cefepime
Brief summary
the aim of this study is to evaluate the efficacy of employing cefepime (CFM) versus ampicillin/sulbactam (AMS) in lowering the rate of post-cesarean surgical site infections.
Detailed description
A prospective randomized clinical study conducted in the department of obstetrics and gynecology of Beni-Suef University Hospital . A total of 213 women were assessed for eligibility, 13 of which were excluded. A total of 200 pregnant women who were eligible for elective cesarean sections (CS). The overall median duration of postoperative followed up was from 10 days to one month to determine the surgical site infection (SSI).
Interventions
DRUGCefepime 1000 MG
Cefepime is a fourth-generation cephalosporin antibiotic
Broad-Spectrum Antibiotic
Sponsors
Beni-Suef University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Pregnant women within age group more than18 years. * Pregnant women with elective cesarean delivery. * Previous and primary cesarean delivery.
Exclusion criteria
Severe hepatic disease women Emergent cesarean deliveries. Women with medical disorders as pre-gestational diabetes, anemia, hypertension, or preeclampsia. Women who had a skin infection adjacent to the operative site.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| surgical site infection | 1 month | pain, redness, swelling, warm skin around the wound, yellow or green discharge |
Countries
Egypt
Outcome results
None listed