ST Elevation Myocardial Infarction
Conditions
Keywords
STEMI, Myocardial infarction, acute coronary syndrome, CV mortality, biobanking
Brief summary
This is a national, multicenter prospective observational study of patients presenting to hospitals in Armenia with STEMI diagnosis. The main questions it aims to answer are: * Determine the rate of in-hospital mortality for the patients with STEMI admitted to the participating hospitals. * Compare short and long-term CV and all-cause mortality and hospitalization. * Determine how professional guidelines are followed in real-world situations.
Detailed description
Although the state program on primary percutaneous coronary intervention in ST elevated myocardial infarction, which was launched in 2015 helped to drastically decrease STEMI mortality rates, patients who had survived usually develop heart failure (HF) which leads to increased economic burden for the Armenian healthcare system. The total duration of the study will be 24 months. The target number of the inclusion is 2500 patients. The follow-up period for enrolled patients will be 12 months.
Interventions
No specific intervention
Sponsors
Santé Arménie French-Armenian Research Center
Armenian Cardiologists Association
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Adult patient (≥ 18 years of age), 2. Admitted to the participating centers for a STEMI within 48 hours of symptom onset: characterized by a rise and fall of cardiac markers (troponins) together with ST elevation in at least two contagious leads or LBBB. 3. Have given signed informed consent to participate in the study. Non-Inclusion Criteria: 1. MI occurring ≤ 48 hours after PCI or CABG 2. The patient or the legal representative refused to sign the informed consent
Exclusion criteria
Withdrawal of the informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of the in-hospital mortality | During 5 to 7 days of hospitalization | Determine the rate of the in-hospital mortality for the patients with STEMI admitted to the participating hospitals |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular mortality | 30 days and 12 months | Compare short-term (30 days) and long-term (12 months) CV mortality depending on the management strategies. |
| All-cause mortality | 30 days and 12 months | Compare short-term (30 days) and long-term (12 months) all-cause mortality. |
Countries
Armenia
Contacts
Primary ContactHamlet G Hayrapetyan, Prof.
Backup ContactHripsime V Poghosyan, Dr.
Outcome results
None listed