Seizures
Conditions
Brief summary
Epilepsy is a chronic disease triggered by increased impulsiveness of nerve cells in the brain and may require a lifelong treatment. Epilepsy is confirmed by two or more unprovoked seizures in more than 24 hours. Febrile Convulsion is another type of seizure occurring due to fever over 38 °C without a history of convulsion, CNS infection, electrolyte imbalance, metabolic disorder, intoxication, and trauma. Unlike epileptic seizures, there are non-epileptic seizures such as Breath Holding Spells that affect children's behaviors and often look like epileptic seizures. QT parameters elongation show the danger of dysrhythmia and unexpected sicknesses such as cardiomyopathy, mitral valve prolapse, ischemic coronary illness, and kidney disorders. Many investigators have reported changes in QT parameters in various diseases such as diabetes mellitus, celiac disease, thalassemia , epilepsy ,Breath holding spells and febrile seizure.
Interventions
DEVICEECG
ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG.
Sponsors
Sohag University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* children with drug resistant epilepsy. * febrile seizures. * age of 1 year to 12 years.
Exclusion criteria
* age below 1 year and above 12 years * children with convulsion secondary cns infection , encephalitis, encephalopathy , toxic and metabolic problem
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| QT interval | 12 months | Distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG |
Countries
Egypt
Contacts
Primary ContactAmany K El Zanaty, resident
Backup ContactMohamed M Fawaz, professor
Outcome results
None listed