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Biomarkers and Risk Factors for Perioperative Neurocognitive Dysfunction in Elderly Patients

Biomarkers and Risk Factors for Perioperative Neurocognitive Disorders in Elderly Non-neurosurgical Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06044207
Enrollment
1000
Registered
2023-09-21
Start date
2023-06-01
Completion date
2026-01-01
Last updated
2023-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative Neurocognitive Dysfunction

Brief summary

Basic information and biological samples of patients were collected preoperatively and intraoperatively, and patients were divided into case and control groups by cognitive function assessment postoperatively, and risk factors and biomarkers of perioperative cognitive dysfunction were derived by analyzing and statistically processing basic information and biological samples.

Interventions

The scale is suitable for evaluating sleep quality in patients with sleep disorders and psychiatric disorders, as well as for assessing sleep quality in the general population.

DIAGNOSTIC_TESTSelf-rating depression scale

The scale is easy to use, can fairly intuitively reflect whether the patient has depression and the degree of depression, has been widely used in outpatient gross screening, mood state assessment.

The scale is a tool used for rapid screening of mild cognitive dysfunction to identify patients with preoperative cognitive dysfunction

Sponsors

Jinan Central Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age more than or equal to 65 years old * ASA classification Ⅰ\ Ⅲ grade

Exclusion criteria

* History of previous Craniocerebral surgery or Craniocerebral trauma * Inability to successfully complete preoperative psychological function tests * Those who are severely deaf, speech impaired and otherwise unable to communicate.

Design outcomes

Primary

MeasureTime frameDescription
Perioperative neurocognitive dysfunction1 year postoperativeIdentification of patients who develop perioperative neurocognitive disorders after surgery by postoperative follow-up with cognitive function tests

Countries

China

Contacts

Primary ContactWenying Chi, Master
cwy2907@zxyy.cn18654557772

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026