Optical Coherence Tomography, Optical Coherence Tomography Angiography
Conditions
Keywords
Normative database, Healthy subjects, Optical coherence tomography, Optical coherence tomography angiography, Heidelberg, Vascular density
Brief summary
Optical coherence tomography angiography (OCT-A) is a determinant progress to study retinal and choroidal vasculature without using a dye injection. OCT-A yields interesting results in different pathologies such as diabetes mellitus, age-related macular degeneration, hypertension blood pressure, particularly by affecting vascular density. Normative database are necessary to compare OCT-A parameters between patients and controls. However, OCT-A devices from different manufactures may give different values for the same subject. It seems to be obvious that each OCT-A device should have its own normative database. In the literature, OCT-A normative databases are developing using different types of devices, but none is available for Heidelberg OCT-A in Caucasians. The purpose of this project is to create a normative database of retinal microvascularisation using Spectralis Heidelberg optical coherence tomography angiography (OCT-A) ® in normal controls.
Interventions
OTHEROptical coherence tomography angiography
Optical coherence tomography angiography
ophthalmological exam
Sponsors
GHPSO de Creil
Hôpital Saint Vincent de Paul, Lille
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Voluntary adult subjects or legal representative consenting for minor or subjects under protection * Intra ocular pression ≤ 21mmHg * Spherical refraction comprised between - 6 D and +6 D and/or axial length between 21 and 26mm * Patient affiliated to social security system
Exclusion criteria
* Ocular diseases: glaucoma, retinal diseases as diabetic retinopathy, age-related macular degeneration, amblyopia, optic neuropathy * Diabetes mellitus * Uncontrolled hypertension blood pressure (\> 140/90) * Recent ocular surgery (\< 6 months) * Any ophthalmological conditions interfering with a good ocular examination or OCT quality (cataract, corneal opacity …) * OCT-A sufficient quality ≥ 25 (0 = bad quality /40 = excellent quality * Not consenting patient * Pathological situation or handicap avoiding good installation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| vascular density of superficial capillary plexus measurement | one day | vascular density of superficial capillary plexus measurement |
| vascular density of deep capillary plexus measurement | one day | vascular density of deep capillary plexus measurement |
| choriocapillaris density in macular zone | one day | choriocapillaris density in macular zone |
| choriocapillaris density in peripapillary zone | one day | choriocapillaris density in peripapillary zone |
Countries
France
Contacts
Primary ContactHa-Chau TRAN, Pr
Outcome results
None listed