Guillain-Barre Syndrome
Conditions
Keywords
Guillain-barre syndrome, prognosis
Brief summary
The goal of this observational study is to explore significant indicators to predict the early prognosis and late prognosis in patients with Guillain-Barre syndrome.
Detailed description
This is a multicenter study(approximately three) with over 450 subjects.Clinical data were collected by consulting the patient's electronic history. The data included demographic information, blood biochemical markers, clinical characteristics and electromyography. All participants provided their written informed consent to participate in this study.
Interventions
patients were treated with intravenous immunoglobulin(30g ivgtt qd) for 5 days
DRUGMethylprednisolone 500 MG Injection
patients were treated with methylprednisolone
Sponsors
First Affiliated Hospital of Wenzhou Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patients fulfilled clinical, biological, and electrophysiology criteria for Guillain-barre syndrome.
Exclusion criteria
* nonidiopathic Guillain-barre syndrome and Miller Fisher syndrome
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the severity of Guillain-barre syndrome | baseline, at 1 week, at 26 weeks | The Guillain-barre syndrome disability score is a wide scale for the severity of Guillain-barre syndrome (0, optimal health; 1, minor symptoms, able to run; 2, able to walk unaided 10 m, unable to run; 3, able to walk 10 m across an open space with help; 4 bedridden or wheelchair users; 5, require assisted ventilation; 6, dead).The higher the score, the worse the prognosis. |
Countries
China
Contacts
Primary ContactBinbin Deng
Outcome results
None listed