Recurrent Extrahepatic Bile Duct Stones as a Late Complication of ERCP in Patients With Coexisting Intra- and Extrahepatic Bile Duct Stones

Recurrent Extrahepatic Bile Duct Stones as a Late Complication of ERCP in Patients With Coexisting Intra- and Extrahepatic Bile Duct Stones：a Long-term Retrospective Cohort Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06041113

Enrollment

104

Registered

2023-09-18

Start date

2023-09-30

Completion date

2024-07-31

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Choledocholithiasis, Intrahepatic Bile Duct Stone

Brief summary

The management of coexisting intrahepatic bile duct (IBD) and extrahepatic bile duct (EBD) stones is complicated and requires a multidisciplinary approach. The long-term clinical outcomes of patients initially treated with endoscopic retrograde cholangiopancreatography (ERCP) EBD stone extraction remain unclear. Investigators conducted a retrospective study of patients with coexisting IBD and EBD to investigate the long-term impact of ERCP on the incidence of recurrent EBD stones and to identify risk factors of recurrence.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* non-gastrointestinal tract reconstruction patients with coexisting IBD and EBD stones who underwent ERCP between July 2008 and December 2020 at Xijing Hospital in China

Exclusion criteria

* patients with benign or malignant EBD strictures * sclerosing cholangitis * suspected choledochal cysts * liver cirrhosis * parasitic liver diseases * long-term biliary drainage with biliary stents or percutaneous tubes * without a definitive IBD stone or with a diagnosis of liver calcification as determined by imaging review * medical records or follow-up information was unavailable

Design outcomes

Primary

Measure	Time frame	Description
the recurrence rate of EBD stones	up to 2 years	Stone recurrence was defined as new EBD stone formation beyond 3 months after complete initial clearance.

Countries

China

Contacts

Primary ContactYanglin Pan, MD

yanglinpan@hotmail.com86-29-84771536

Outcome results