Myocardial Infarction, Acute
Conditions
Keywords
TRAF3IP2, Myocardial Infarction, Coronary angiography, MACEs
Brief summary
To evaluate the prognostic value of surem TRAF3IP2 levels in patients with acute myocardial infarction
Detailed description
Previous study had concluded that TRAF3IP2 plays a causal role in atherosclerotic plaque development and vulnerability in mice. However, no human data was available. In the present study, patients diagnosed with acute myocardial infarction who receive coronary angiography will be enrolled. Their surem TRAF3IP2 levels will be tested using ELASA. The association of surem TRAF3IP2 levels with the major adverse cardiac events will be evaluated.
Interventions
OTHERNo intervention
This is an obvertional study, and there is no intervention.
Sponsors
Nanjing Medical University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
1. Patients with acute myocardial infarction 2. patients received coronary angiography 3. invasive management within 72 h of hospital admission
Exclusion criteria
1. NYHA III-IV 2. malignant tumor 3. acute infection 4. thyroid dysfunction 5. Life expectancy of b1 y 6. Unsuitable for PCI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MACEs (major adverse cardiac events) | 1 year | MACEs were defined as a composite of cardiac death, hospitalization for myocardial infarction or heart failure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| cardiac death | 1 year | and death due to cardiac reasons, such as myocardial infarction or heart failure |
| hospitalization for myocardial infarction or heart failure | 1 year | hospitalization for myocardial infarction or heart failure |
Countries
China
Contacts
Primary ContactJin Geng, MD.
Outcome results
None listed