Esophageal Cancer
Conditions
Keywords
radiation
Brief summary
The goal of this clinical trial is to test the use of CPAP in patients with esophgaeal cancer undergoing radiotherapy. The main questions it aims to answer are: * does use of CPAP decrease exposure of normal lung to radiation? * does use of CPAP decrease exposure of normal heart to radiation? Participants will undergo simulation twice: * with CPAP * without CPAP
Interventions
DEVICECPAP
patients undergo simulation twice, with and without CPAP
Sponsors
Sheba Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
all patients undergo two simulations.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Diagnosis of cancer, with a tumor (primary or secondary) in the esophagus including tumors in the esophagus-stomach junction. 2. Age ≥ 18 3. Planned RT treatment 4. The level of functioning ≥ 60 on the Karnofsky scale 5. Life expectancy ≥ two months 6. All patients must understand the informed consent form document and sign it of their own free will before any test/procedure related to the study is performed. 7. Able to undergo simulation and radiation with CPAP 8. Candidate patients can be recruited to receive definitive, palliative or pre-operative radiation, with or without chemotherapy.
Exclusion criteria
A person who meets any of the following
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| absolute mean heart radiation dose | on day of simulation (day 1) | measured in Gy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| lung dose in Gy | on day of simulation (day 1) | mean lung dose, V5 and V20 |
| heart dose in Gy | on day of simulation (day 1) | mean heart dose, V30 |
| movement of tumor in cm | on day of simulation (day 1) | how much tumor moves with breathing |
Countries
Israel
Outcome results
None listed