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Deep Learning Image Reconstruction for Abdominal CT of Hepatocellular Carcinoma Compared With 3-TESLA MRI

Deep Learning Image Reconstruction for Abdominal CT of Hepatocellular Carcinoma Compared With 3-TESLA MRI

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06037343
Enrollment
50
Registered
2023-09-14
Start date
2023-02-23
Completion date
2023-12-30
Last updated
2025-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma

Keywords

Hepatocellular carcinoma, DLIR CT, ASIR reconstruction

Brief summary

New algorithms for processing CT acquisitions, based on artificial intelligence, have been reported to improve acquisition quality. Thats' why it's possible to imagine that new scan post-processing algorithms enable better detection and characterization of hepatocellular carcinoma lesions than with standard reconstructions. DLIR reconstructions could even match with MRI detection. The aim of the study is to compare the detection and characterization of hepatic lesions according to the LI-RADS classification in CT with DLIR artificial intelligence reconstruction, compared with ASIR-V reconstruction and the gold standard of MRI.

Interventions

None listed

Sponsors

Central Hospital, Nancy, France
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* undergoing CT and MRI scans in the same week, with protocols dedicated to the detection of HCC lesions

Exclusion criteria

* imaging with radiological artefact

Design outcomes

Primary

MeasureTime frameDescription
Lesion size in mmThrough study completion, an average of 1 year
Hypervascular appearance of lesionThrough study completion an average of 1 yearQualitative measurement: presence or absence of hypervascular lesion
Hypervascular capsuleThrough study completion an average of 1 yearQualitative measurement : presence or absence of hypervascular capsule

Secondary

MeasureTime frame
Infiltrative nature Classification of the hepatic lesion by LI-RADS in MRIThrough study completion an average of 1 year

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026